Evidence map›Paper›PMID 32222455›Full record

ArticleExperimental eye research2020

Effect of prostaglandin analogs: Latanoprost, bimatoprost, and unoprostone on matrix metalloproteinases and their inhibitors in human trabecular meshwork endothelial cells.

Jae Young Heo, Yen Hoong Ooi, Douglas J Rhee

Open access · greenAbstract read
In one paragraph

Article in Experimental eye research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Cystoid macular edema following travoprost intracameral implant.American journal of ophthalmology case reports · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. From Eye Care to Hair Growth: Bimatoprost.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jae Young HeoDepartment of Ophthalmology, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH, 44106, USA.
Yen Hoong OoiDepartment of Pediatrics, New York Downtown Hospital, 83 Gold Street, New York, NY, 10038, USA.
Douglas J RheeDepartment of Ophthalmology, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH, 44106, USA. Electronic address: Douglas.Rhee@uhhospitals.org.
University Hospitals of Cleveland · USLower Manhattan Hospital · US

Funding

TISSUE CULTURE AND HYBRIDOMA MODULEP30EY011373 · NEI · CASE WESTERN RESERVE UNIVERSITY · PI Irina A Pikuleva · 1997 to 2026
$17.7M
Matricellular Proteins in Trabecular Meshwork Increase Intraocular PressureR01EY019654 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI RHEE, DOUGLAS J · 2009 to 2020
$3.5M
NEI NIH HHS P30 EY011373NEI NIH HHS R01 EY019654
6 · The paper itself

Abstract

Bimatoprost, latanoprost, and unoprostone are prostaglandin F

Indexed as

AdultAgedAntihypertensive AgentsBimatoprostCells, CulturedFemaleGlaucoma, Open-AngleHumansImmunoblottingLatanoprostMaleMatrix Metalloproteinase InhibitorsMatrix MetalloproteinasesMiddle AgedOphthalmic SolutionsProstaglandins A, SyntheticAntihypertensive AgentsBimatoprostdiponiumLatanoprostMatrix Metalloproteinase InhibitorsMatrix MetalloproteinasesOphthalmic SolutionsProstaglandins A, SyntheticQuaternary Ammonium CompoundsGlaucomaMatrix metalloproteinasesOpen-angle glaucomaProstaglandin analogsTissue inhibitors of metalloproteinasesTrabecular meshwork endothelial cellsTranscriptional expression

Identifiers

PMID32222455
PMCPMC7262744
OpenAlexW3013856584

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.