Evidence map›Paper›PMID 32222443›Full record

SynthesisJACC. Cardiovascular interventions2020

Fractional Flow Reserve-Based Coronary Artery Bypass Surgery: Current Evidence and Future Directions.

Cristiano Spadaccio, David Glineur, Emanuele Barbato, Antonino Di Franco, Keith G Oldroyd, Giuseppe Biondi-Zoccai, Filippo Crea, Stephen E Fremes, Dominick J Angiolillo, Mario Gaudino

Registry-linked trialOpen access · greenAbstract readSystematic Review
In one paragraph

Synthesis in JACC. Cardiovascular interventions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04379947 (A Real Life All-comers Retrospective Study on FFR-based CABG), which is not on this map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04379947 withdrawnnot on this map

A Real Life All-comers Retrospective Study on FFR-based CABG

TypeobservationalSponsorUniversity of GlasgowRan2020 to 2021Enrolled0ConditionsFracational Flow Reserve, Coronary Artery Disease, Coronary Artery Bypass SurgeryArmsFractional Flow reserve
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Observational
  16. Article
  17. Understanding the mechanism of improved CFR after TAVR/SAVR - the importance of basal flow.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 4 countries.

Cristiano SpadaccioDepartment of Cardiothoracic Surgery, Golden Jubilee National Hospital, Glasgow, United Kingdom.
David GlineurDivision of Cardiac Surgery, University of Ottawa, Ottawa, Ontario, Canada.
Emanuele BarbatoDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Napoli, Italy.
Antonino Di FrancoDepartment of Cardiothoracic Surgery, Weill Cornell Medicine, New York, New York.
Keith G OldroydWest of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Glasgow, United Kingdom.
Giuseppe Biondi-ZoccaiDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy; Mediterranea Cardiocentro, Napoli, Italy.
Filippo CreaDepartment of Cardiovascular and Thoracic Sciences, IRCCS Fondazione Policlinico Universitario A. Gemelli, Rome, Italy.
Stephen E FremesSchulich Heart Centre, Division of Cardiac Surgery, Department of Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Dominick J AngiolilloDepartment of Cardiology, University of Florida College of Medicine, Jacksonville, Florida.
Mario GaudinoDepartment of Cardiothoracic Surgery, Weill Cornell Medicine, New York, New York. Electronic address: mfg9004@med.cornell.edu.
Cornell University · USGolden Jubilee National Hospital · GBAgostino Gemelli University Polyclinic · ITClinica Mediterranea · ITSunnybrook Health Science Centre · CAUniversity of Florida · USUniversity of Naples Federico II · ITUniversity of Ottawa · CA

Funding

Randomized comparison of the clinical Outcome of single versus Multiple Arterial grafts: Quality of Life (ROMA:QOL)R01HL152021 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI GAUDINO, MARIO FL, MASTERSON CREBER, RUTH MARIE · 2020 to 2024
$4.1M
NHLBI NIH HHS R01 HL152021
6 · The paper itself

Abstract

Fractional flow reserve (FFR) provides an objective measurement of the severity of ischemia caused by coronary stenoses in downstream myocardial regions. Data from the interventional cardiology realm have suggested benefits of a FFR-guided percutaneous coronary intervention (PCI) strategy. Limited evidence is available on the use of FFR to guide coronary artery bypass grafting (CABG). The most recent data have shown that FFR might simplify CABG procedures and optimize patency of arterial grafts without any clear impact on clinical outcomes. The aim of this review was to summarize the available data on FFR-based CABG and discuss the rationale and potential consequences of a switch toward FFR-based surgical revascularization strategy.

Indexed as

Cardiac CatheterizationCoronary Artery BypassFractional Flow Reserve, MyocardialCoronary AngiographyCoronary Artery DiseaseHumansPredictive Value of TestsTreatment OutcomeVascular PatencyCABGFFRmyocardial revascularization

Identifiers

PMID32222443
PMCPMC7826159
OpenAlexW3013433500

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.