Evidence map›Paper›PMID 32222410›Full record

ArticleThe Journal of thoracic and cardiovascular surgery2021

Simple 2-dimensional anatomic model to predict the risk of coronary obstruction during transcatheter aortic valve replacement.

Megan Heitkemper, Srikrishna Sivakumar, Hoda Hatoum, Jennifer Dollery, Scott M Lilly, Lakshmi Prasad Dasi

Open access · greenAbstract read
In one paragraph

Article in The Journal of thoracic and cardiovascular surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Lifetime management of patients with symptomatic severe aortic stenosis: a computed tomography simulation study.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022
    Trial
  2. Article
  3. [A case of coronary artery protection in transcatheter aortic valve replacement of quadricuspid aortic valve].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Megan HeitkemperDepartment of Biomedical Engineering, The Ohio State University, Columbus, Ohio.
Srikrishna SivakumarDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga.
Hoda HatoumDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga.
Jennifer DolleryDivision of Cardiology, The Ohio State University, Columbus, Ohio.
Scott M LillyDivision of Cardiology, The Ohio State University, Columbus, Ohio.
Lakshmi Prasad DasiDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga. Electronic address: lakshmi.dasi@gatech.edu.
The Ohio State University · USGeorgia Institute of Technology · US

Funding

Superhydrophobic Heart Valve ProsthesisR01HL135505 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD, KOTA, ARUN KUMAR · 2017 to 2020
$2.9M
Hyaluronan enhanced polymeric heart valve prosthesisR01HL119824 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD · 2013 to 2017
$1.7M
Superomniphobic flow controlled prosthetic heart valveR21HL139208 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD, KOTA, ARUN KUMAR · 2018 to 2019
$408k
NHLBI NIH HHS R01 HL119824NHLBI NIH HHS R01 HL135505NHLBI NIH HHS R21 HL139208
6 · The paper itself

Abstract

objectiveIn this study, a 2-dimensional (2D) index relying on preprocedural computed tomography (CT) data was developed to evaluate the risk of coronary obstruction during transcatheter aortic valve replacement (TAVR) procedures.

methodsAnatomic measurements from pre-TAVR CT scans were collected in 28 patients among 600 who were flagged as high risk (defined as meeting coronary artery height, h, <14 mm and/or sinus of Valsalva diameter, SOVd, <30 mm) for coronary obstruction. A geometric model derived from these anatomic measurements was used to predict the post-TAVR native cusp apposition relative to the coronary ostium. The distance from the cusp to the coronary ostium, DLC

resultsTwenty-three of 28 high-risk patients successfully underwent TAVR without coronary obstruction, of whom 1 had coronary obstruction and 4 were deemed non-TAVR candidates. DLC

conclusionsThe 2D geometric model derived in this study shows promise for identifying patients with low-lying coronary ostium and/or small SOVd that may be safely treated with TAVR. DLC

Indexed as

Coronary VesselsTranscatheter Aortic Valve ReplacementAgedAortic Valve StenosisComputed Tomography AngiographyCoronary OcclusionFemaleHumansIntraoperative ComplicationsMaleModels, AnatomicPatient-Specific ModelingPreoperative CareRisk AdjustmentTomography, X-Ray ComputedTreatment Outcomecalcificationcoronary obstructionFEApatient-specificTAVR

Identifiers

PMID32222410
PMCPMC7434688
OpenAlexW3007689850

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.