ReviewProgress in cardiovascular diseases
Postural Orthostatic Tachycardia Syndrome (POTS): A critical assessment.
Review in Progress in cardiovascular diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.
- Use of Ivabradine in the Treatment of Patients with Postural Orthostatic Tachycardia Syndrome (POTS): A Systematic Review.Arquivos brasileiros de cardiologia · 2025Pooled it
- Top developments in clinical cardiac electrophysiology-2025.Heart rhythm O2 · 2026Review
- Cardiovascular Health in Women-Across the Lifespan.Clinical endocrinology · 2026Review
- Impact of Excessive Postural Tachycardia on Disability in Youth with Orthostatic Intolerance.The Journal of pediatrics · 2026Article
- Utilization of machine learning in diagnosis of postural tachycardia syndrome (POTS).Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Article
- Postural Orthostatic Tachycardia Syndrome Presenting With Recurrent Syncope After Cervical Spinal Cord Injury.Clinical case reports · 2026Article
- Review of published research on primary dysautonomia of domestic animals.The Veterinary record · 2026Review
- Prevalence of Central Sensitization in Postural Tachycardia Syndrome.JAMA network open · 2026Article
- Neurocardiac Crosstalk: Sympathetic Remodeling and Arrhythmogenesis After Myocardial Infarction.Current issues in molecular biology · 2025Review
- Autoimmune Antibodies in Orthostatic Intolerance Syndromes.Physiological research · 2025Article
- Analysis of Factors Relevant to the Severity of Symptoms in Children and Adolescents with Postural Orthostatic Tachycardia Syndrome.Children (Basel, Switzerland) · 2025Article
- Pathophysiology of functional neurological disorder for the general neurologist.BMJ neurology open · 2025Review
- Differential diagnosis of orthostatic dizziness with persistent postural-perceptual dizziness and its underlying mechanisms.Frontiers in neurology · 2025Review
- Digital twin framework for postural tachycardia syndrome and autonomic disorders.Frontiers in neurology · 2025Article
- Cerebral blood flow and end-tidal CONeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- The relationship between cardiovagal baroreflex and cerebral autoregulation in postural orthostatic tachycardia disorder using advanced cross-correlation function.Scientific reports · 2024Article
- Article
- Cardiovascular autonomic dysfunction in post-COVID-19 syndrome: a major health-care burden.Nature reviews. Cardiology · 2024Review
- Comment to the article "Standing tests lack reliability to diagnose all adolescents who have postural tachycardia syndrome".Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024Article
- Cardiovascular effects of the post-COVID-19 condition.Nature cardiovascular research · 2024Review
Corrections and comments
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Authors and funding
13 authors at 10 institutions in 3 countries.
Funding
Abstract
Although diagnostic criteria have been developed characterizing postural orthostatic tachycardia syndrome (POTS), no single set of criteria is universally accepted. Furthermore, there are gaps in the present criteria used to identify individuals who have this condition. The reproducibility of the physiological findings, the relationship of symptoms to physiological findings, the presence of symptoms alone without any physiological findings and the response to various interventions confuse rather than clarify this condition. As many disease entities can be confused with POTS, it becomes critical to identify what this syndrome is. What appears to be POTS may be an underlying condition that requires specific therapy. POTS is not simply orthostatic intolerance and symptoms or intermittent orthostatic tachycardia but the syndrome needs to be characterized over time and with reproducibility. Here we address critical issues regarding the pathophysiology and diagnosis of POTS in an attempt to arrive at a rational approach to categorize the syndrome with the hope that it may help both better identify individuals and better understand approaches to therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.