ReviewClinics in geriatric medicine2020
Cognitive Reserve from the Perspective of Preclinical Alzheimer Disease: 2020 Update.
Review in Clinics in geriatric medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Cognitive reserve and everyday functioning in cognitively unimpaired older adults: evidence from the CAN-PROTECT study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Cognitive Reserve as a Protective Factor for Visuospatial Ability in Healthy Aging.Healthcare (Basel, Switzerland) · 2025Article
- The Association Between Multilingual Experience Factors and Cognitive Functioning in Older Adults: A Lifelines Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Linking cognitive and behavioral reserve: Evidence from the CAN-PROTECT study.Alzheimer's & dementia (New York, N. Y.) · 2024Article
- Which intellectual activities are related to cognitive reserve? Introduction and testing a three-dimensional model.Psychological research · 2024Article
- Mechanisms and Functions of the Cerebral-Cognitive Reserve in Patients with Alzheimer's Disease: A Narrative Review.Consortium psychiatricum · 2024Review
- Alzheimer's disease genetic risk and cognitive reserve in relationship to long-term cognitive trajectories among cognitively normal individuals.Alzheimer's research & therapy · 2023Article
- Connectome-based predictive modelling of cognitive reserve using task-based functional connectivity.The European journal of neuroscience · 2023Article
- Greater cognitive reserve is related to lower cortical excitability in healthy cognitive aging, but not in early clinical Alzheimer's disease.Frontiers in human neuroscience · 2023Article
- Inter- and intra-individual variation in brain structural-cognition relationships in aging.NeuroImage · 2022Article
- Quantitative MRI Evidence for Cognitive Reserve in Healthy Elders and Prodromal Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2022Article
- Longitudinal CSF Alzheimer's disease biomarker changes from middle age to late adulthood.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- The Chinese Translation Study of the Cognitive Reserve Index Questionnaire.Frontiers in psychology · 2022Article
- Cognitive and brain reserve predict decline in adverse driving behaviors among cognitively normal older adults.Frontiers in psychology · 2022Article
- Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve.Frontiers in psychology · 2022Article
- Age, vascular disease, and Alzheimer's disease pathologies in amyloid negative elderly adults.Alzheimer's research & therapy · 2021Article
- Longitudinal Analysis of Brain-Predicted Age in Amnestic and Non-amnestic Sporadic Early-Onset Alzheimer's Disease.Frontiers in aging neuroscience · 2021Article
- The Genetic Research in Alzheimer Disease (GERALD) Initiative Finds rs9320913 as a Neural eQTL of lincRNA AL589740.1.International journal of Alzheimer's disease · 2021Article
- Positive Effects of Education on Cognitive Functioning Depend on Clinical Status and Neuropathological Severity.Frontiers in human neuroscience · 2021Article
- Interaction between Cognitive Reserve and Biomarkers in Alzheimer Disease.International journal of molecular sciences · 2020Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The concept of cognitive reserve (CR) was proposed to account for the discrepancy between levels of brain pathologic process or damage and clinical and cognitive function. We provide a detailed review of prospective longitudinal studies that have investigated the interaction between CR and Alzheimer disease (AD) biomarkers on clinical and cognitive outcomes among individuals with normal cognition at baseline. Current evidence is consistent with the view that higher levels of CR are associated with a delay in the onset of symptoms of mild cognitive impairment and that there may be multiple pathways by which CR exerts its protective effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.