Evidence map›Paper›PMID 32222145›Full record

ArticleNutrition journal2020

Association of dietary ω-3 and ω-6 fatty acids intake with cognitive performance in older adults: National Health and nutrition examination Survey (NHANES) 2011-2014.

Xue Dong, Shiru Li, Jiahao Chen, Yan Li, Yanjun Wu, Dongfeng Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrition journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xue DongDepartment of Epidemiology and Health Statistics, School of Public Health, Qingdao University, 38 Deng Zhou Street, Qingdao, 266021, Shandong Province, China.
Shiru LiDepartment of Epidemiology and Health Statistics, School of Public Health, Qingdao University, 38 Deng Zhou Street, Qingdao, 266021, Shandong Province, China.
Jiahao ChenDepartment of Epidemiology and Health Statistics, School of Public Health, Qingdao University, 38 Deng Zhou Street, Qingdao, 266021, Shandong Province, China.
Yan LiDepartment of Epidemiology and Health Statistics, School of Public Health, Qingdao University, 38 Deng Zhou Street, Qingdao, 266021, Shandong Province, China.
Yanjun WuDepartment of Epidemiology and Health Statistics, School of Public Health, Qingdao University, 38 Deng Zhou Street, Qingdao, 266021, Shandong Province, China.
Dongfeng ZhangDepartment of Epidemiology and Health Statistics, School of Public Health, Qingdao University, 38 Deng Zhou Street, Qingdao, 266021, Shandong Province, China. zhangdf1961@126.com.
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent evidence on the association of dietary ω-3 and ω-6 fatty acids intake with cognitive performance is inconsistent. Therefore, the aim is to explore the association of dietary ω-3 and ω-6 fatty acids intake with cognitive performance in the U.S. noninstitutionalized population of older adults.

methodsWe used data from the National Health and Nutrition Examination Survey (NHANES) 2011-2014. Intakes of ω-3 and ω-6 fatty acids were obtained through two 24-h dietary recalls and were adjusted by energy. Cognitive performance was evaluated by the Consortium to Establish a Registry for Alzheimer's disease (CERAD) Word Learning sub-test, Animal Fluency test and Digit Symbol Substitution Test (DSST). For each cognitive test, people who scored lower than the lowest quartile in each age group were defined as having low cognitive performance. Binary logistic regression and restricted cubic spline models were applied to evaluate the association of dietary ω-3 and ω-6 fatty acids intake with cognitive performance.

resultsA total of 2496 participants aged 60 years or older were included. In the full-adjusted model, the odds ratios (ORs) with 95% confidence interval (CI) of CERAD test score, Animal Fluency test score and DSST test score were 0.58 (0.38-0.88), 0.68 (0.47-0.99) and 0.59 (0.37-0.92) for the highest versus lowest tertile of dietary ω-3 fatty acids intake, respectively; the ORs with 95% CI of CERAD test score, Animal Fluency test score and DSST test score were 0.48 (0.31-0.75), 0.60 (0.40-0.92) and 0.50 (0.34-0.75) for the highest versus lowest tertile of dietary ω-6 fatty acids intake, respectively. The association between ω-6: ω-3 ratio and cognitive performance was not statistically significant in three tests. In dose-response relationship analysis, L-shaped associations were apparent for ω-3 and ω-6 fatty acids intake with CERAD test score, Animal Fluency test score and DSST test score.

conclusionsDietary ω-3 and ω-6 fatty acids intake might be inversely associated with low cognitive performance.

Indexed as

AgedAged, 80 and overCognitionCognitive DysfunctionCross-Sectional StudiesDietFatty Acids, Omega-3Fatty Acids, Omega-6FemaleGeriatric AssessmentHealth SurveysHumansMaleMiddle AgedNeuropsychological TestsUnited StatesFatty Acids, Omega-3Fatty Acids, Omega-6Cognitive performanceDietary ω-3 fatty acidsDietary ω-6 fatty acidsDose-responseω-6: ω-3 ratio

Identifiers

PMID32222145
PMCPMC7103069
OpenAlexW3013313217

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.