Evidence map›Paper›PMID 32222079›Full record

Trial reportJournal of child psychology and psychiatry, and allied disciplines2020

Social communication deficits following early-life deprivation and relation to psychopathology: a randomized clinical trial of foster care.

Mark Wade, Charles H Zeanah, Nathan A Fox, Charles A Nelson

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of child psychology and psychiatry, and allied disciplines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Mark WadeDepartment of Applied Psychology and Human Development, University of Toronto, Toronto, ON, Canada.
Charles H ZeanahDepartment of Psychiatry and Behavioral Sciences, Tulane University School of Medicine, New Orleans, LA, USA.
Nathan A FoxDepartment of Human Development and Quantitative Methodology, University of Maryland, College Park, MD, USA.
Charles A NelsonBoston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Boston Children's Hospital · USTulane University · USUniversity of Maryland, College Park · USUniversity of Toronto · CA

Funding

The Relation Between Early Psychosocial Deprivation and Mental Health at 12 YearsR01MH091363 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI FOX, NATHAN A, NELSON, CHARLES ALEXANDER · 2010 to 2024
$9.2M
NIMH NIH HHS R01 MH091363NIMH NIH HHS R01MH091363
6 · The paper itself

Abstract

backgroundChildren reared in institutions experience profound deprivation that is linked to impairments in social communication (SC). However, little is known about the long-term consequences of institutional rearing on SC through adolescence, and how SC deficits relate to broad-spectrum psychopathology. It is also unclear whether early removal from deprivation and placement into socially enriched environments remediates these difficulties.

methodsChildren reared in Romanian institutions from the Bucharest Early Intervention Project were randomly assigned to care as usual or foster care intervention in early childhood. An age- and sex-matched group of never-institutionalized children was also recruited. SC data from 208 children at age 8 and 129 children at 16 were collected using the Social Communication Questionnaire. Psychopathology was assessed as saved factor scores for general (P) and specific internalizing (INT) and externalizing (EXT) problems. We examined (a) whether institutional rearing is associated with continued SC deficits into adolescence; (b) whether early placement into foster care mitigates risk for SC problems; and (c) associations between SC and psychopathology from middle childhood (age 8) to adolescence (age 16).

resultsFindings suggest that: (a) institutionally-reared children have significantly more SC problems than never-institutionalized children at age 16; (b) children placed into foster care early in life have fewer problems with reciprocal social interaction compared to those with prolonged institutional rearing; and (c) deficits in SC at age 8 partially account for the link between institutional rearing and general psychopathology at age 16.

conclusionsEarly deprivation is associated with impairments in SC that persist into adolescence, with evidence for the remedial benefit of family-based care in the domain of reciprocal social interaction. Moreover, deficits in SC among ever-institutionalized children in middle childhood may increase the risk of broad-spectrum psychopathology in adolescence, thus providing one putative target for early intervention to safeguard against later psychiatric problems.

Indexed as

CommunicationPsychopathologySocial InteractionAdolescentChildChild DevelopmentChild, InstitutionalizedChild, PreschoolFemaleFoster Home CareHumansMaleMental DisordersPsychology, ChildRomaniafoster care interventionInstitutional rearingmaltreatmentpsychopathologysevere early neglectsocial communication

Identifiers

PMID32222079
PMCPMC7967662
OpenAlexW3013828662

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.