ArticleJournal of clinical laboratory analysis2020
Use of complete blood count for predicting preterm birth in asymptomatic pregnant women: A propensity score-matched analysis.
Article in Journal of clinical laboratory analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Relationship between Platelet-to-Lymphocyte Ratio and Lymphocyte-to-Monocyte Ratio with Spontaneous Preterm Birth: A Systematic Review and Meta-analysis.Journal of immunology research · 2023Pooled it
- Is there a maternal blood biomarker that can predict spontaneous preterm birth prior to labour onset? A systematic review.PloS one · 2022Pooled it
- The Association of Inflammatory Biomarker of Neutrophil-to-Lymphocyte Ratio with Spontaneous Preterm Delivery: A Systematic Review and Meta-analysis.Mediators of inflammation · 2021Pooled it
- Complete Blood Count Parameters and Hemogram-Derived Inflammatory Indices in Adolescent Pregnancy: A Retrospective Comparative Cohort Study with Exploratory Machine-Learning Analyses.Journal of clinical medicine · 2026Article
- Article
- The association of inflammatory markers with cerclage failure in twin pregnancies.BMC pregnancy and childbirth · 2026Article
- Hematologic Ratios as Early Biomarkers for Preterm Premature Rupture of Membranes: A Prospective Cohort Study.Cureus · 2026Article
- Predictive Value of Neutrophils, Lymphocytes, Platelets, Neutrophil-Lymphocyte Ratio (NLR), and Platelets-Lymphocyte Ratio (PLR) in Preterm Labor: Single and Combined Indices.Obstetrics and gynecology international · 2026Article
- Clinical utility of calculated haematological parameters in the diagnosis of iron deficiency anaemia in pregnant women.Biomedical reports · 2025Article
- Association of periodontal diseases with inflammatory markers and gestational diabetes: a case-control study.BMC oral health · 2025Article
- Physiological Changes and Trimester-Specific Reference Intervals for Complete Blood Count Parameters in Korean Pregnant Women.Medicina (Kaunas, Lithuania) · 2025Article
- Relationship between serum ferritin and proinflammatory markers in late pregnancy: An exploratory analysis from Cartagena, ColombiaBiomedica : revista del Instituto Nacional de Salud · 2025Article
- The relationship between maternal oral health parameters, inflammatory blood markers, and the evaluation of their effects on preterm low birth weight.BMC pregnancy and childbirth · 2025Article
- The single-cell immune profile throughout gestation and its potential value for identifying women at risk for spontaneous preterm birth.European journal of obstetrics & gynecology and reproductive biology: X · 2025Review
- Early hematological indices as a predictor of placenta accreta in women with high suspicion of accreta.Medicine · 2025Observational
- Predictive Role of Maternal Laboratory Parameters and Inflammatory Scores in Determining Systemic Inflammatory Response Syndrome in Newborns at Birth.Journal of personalized medicine · 2024Article
- The relationships of inflammatory blood markers with maternal periodontal and dental states and their effects on preterm membrane rupture development.BMC oral health · 2024Article
- Predicting Spontaneous Preterm Birth Using the Immunome.Clinics in perinatology · 2024Review
- Identification of novel cell-free RNAs in maternal plasma as preterm biomarkers in combination with placental RNA profiles.Journal of translational medicine · 2023Article
- Assessing the Utility of Hemoglobin, HALP Score, FAR Ratio, and Coagulation Parameters as Predictors for Preterm Birth.Children (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundAccurate prediction of preterm birth (PTB) is still difficult, mostly because of the multifactorial etiology of PTB. Previous studies have been mostly focused on the prediction of PTB in symptomatic women or those presenting with threatened preterm labor. We aimed to study whether complete blood count (CBC) parameters at 20-30 weeks of pregnancy can predict asymptomatic PTB.
methodsIn this retrospective case-control study, the preterm and term delivery groups were matched by propensity score-matched (PSM) analysis. Baseline data and the CBC parameters examined at 20-30 weeks of gestation were recorded.
resultsThe combined marker of neutrophil-to-lymphocyte ratio (NLR), hemoglobin (HGB), and platelet distribution width (PDW) accurately predicts PTB at a cutoff value of 0.25, with sensitivity and specificity of 88.6% and 40.5% and negative and positive predictive value of 97.9% and 10.2%, respectively.
conclusionThe combined marker of CBC parameters can supplement other markers to predict PTB about 10 weeks in advance. This combined marker had a very high negative predictive value for PTB. Therefore, in subjects with normal combined marker value, further screening tests for PTB may be eliminated unless clinical suspicion is high.
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