ArticleMethods in molecular biology (Clifton, N.J.)2020
In Vitro Culture for Differentiation Simulation of Leishmania spp.
Article in Methods in molecular biology (Clifton, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The trial behind it
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Who cites it
6 citing papers in PubMed.
- Identification of novel inhibitors from3 Biotech · 2025Article
- Morphogenesis Dynamics in Leishmania Differentiation.Pathogens (Basel, Switzerland) · 2022Article
- Finding Correlations Between mRNA and Protein Levels inFrontiers in cellular and infection microbiology · 2022Review
- Leishmania donovani Metacyclic Promastigotes Impair Phagosome Properties in Inflammatory Monocytes.Infection and immunity · 2021Article
- TheFrontiers in cellular and infection microbiology · 2021Article
- Lysosome Sensing Is a Key Mechanism inFrontiers in microbiology · 2021Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the 1990s my laboratory discovered that Leishmania promastigotes can combine two environmental cues, typical to lysosomes, acidic pH (~5.5) and body temperature (37 °C) into a single signal that induced differentiation. Based on this concept, we modified EARLS-based medium 199 to become an amastigote-specific medium. Shifting promastigotes to this medium followed by incubation in a CO
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Registered trials
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