Observational studyEuropean radiology2020
Absorbable stents for treatment of benign biliary strictures: long-term follow-up in the prospective Spanish registry.
Observational study in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Safety and Efficacy of Absorbable Biliary Stents for Benign Bile Duct Strictures: A Systematic Review and Meta-Analysis.Cardiovascular and interventional radiology · 2026Pooled it
- Functionalized bioresorbable biliary stents: materials design, coating engineering, and clinical translation.RSC advances · 2026Review
- The safety and efficacy of the percutaneous balloon-expandable biodegradable magnesium biliary stents in patients with liver transplant.Diagnostic and interventional radiology (Ankara, Turkey) · 2026Article
- Biodegradable stents for biliary strictures after pediatric liver transplantation: a multicenter retrospective study.European radiology · 2026Article
- Clinical Outcomes of Retained Plastic Biliary Stents: A Targeted Narrative Review.Digestive diseases and sciences · 2026Review
- Biosynthetic Plastics as Tunable Elastic and Visible Stent with Shape-Memory to Treat Biliary Stricture.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Stepwise Percutaneous Approach to Treat Severe Benign Hepaticojejunostomy Stenosis.Seminars in interventional radiology · 2022Review
- A New Biodegradable Stent to Improve the Management of Biliary Strictures in Pediatric Split Liver Transplantation.Cardiovascular and interventional radiology · 2022Article
- Endoscopic treatment of benign biliary stricture using different stents: a systematic review and meta-analysis.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022Article
- Article
- Bio-Degradable Stents: Primary Experience in a Tertiary Hepatopancreaticobiliary Center in the United Kingdom.Cureus · 2021Article
- Percutaneous Management of Benign Biliary Strictures.Seminars in interventional radiology · 2021Review
- Interventional radiology for liver diseases.European radiology · 2021Article
- Early Biodegradable Stent Placement for Percutaneous Hepaticojejunostomy Stricture Management.Journal of clinical and experimental hepatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesBenign strictures of the bile duct may be difficult to treat endoscopically due to altered bowel anatomy. Furthermore, recurrence of stenosis and symptoms remains high. The aim of the Spanish Prospective Registry BiELLA study was to investigate the safety and efficacy of absorbable stents in the treatment of benign biliary strictures and their outcomes on the medium and long-term follow-up.
methodsA prospective, multicenter, observational, non-randomized study (the BiELLA study) was conducted from January 2014 to September 2018. One hundred fifty-nine patients with benign biliary strictures, mostly postsurgical, were enrolled for implantation of absorbable biliary stents in the 11 participating Spanish tertiary hospitals. The average patient follow-up was 45.4 ± 15.9 months (range, 12-60 months). The follow-up data included symptoms, biochemical parameters, and ultrasound images at 1, 6, and 12 months and then yearly for up to 60 months.
resultsThe immediate technical and clinical success rates were 100%. In all patients, stent placement resulted in improvement of clinical symptoms and biochemical parameters. The primary mean patency for stent was 86.7, 79.6, and 78.9% at 12, 36, and 60 months, respectively (95% CI). Biliary restenosis and occlusion occurred in 40 (26.6%) patients. Of the 40 patients, 18 (12%) patients were treated with a second stent and 22 (14.6%) patients had operative repair of the recurrent strictures. There were no major complications associated with stent implantation.
conclusionsImplantation of an absorbable polydioxanone biliary stent is safe and effective for treatment of benign biliary strictures refractory to balloon dilatation or other biliary intervention. KEY POINTS: • Percutaneous implantation of biodegradable prostheses for the treatment of benign postsurgical biliary strictures is a safe and effective procedure. • More than 75% of the patients presented patency of the stented biliary tree at 5 years follow-up. • Absorbable stents improved clinical symptoms and signs (jaundice, itching, fever), and laboratory parameters in a few days after stent placement.
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