ArticleThe international journal of neuropsychopharmacology2020
Neural Basis of Smoking-Related Difficulties in Emotion Regulation.
Article in The international journal of neuropsychopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Tobacco Use, Stigma, and Coping in Lung Cancer: A Systematic Review of Their Psychosocial Interactions and Clinical Implications.Current oncology (Toronto, Ont.) · 2026Pooled it
- Substance use disorder and altered hemispheric asymmetries: A systematic review.Clinical psychology review · 2025Pooled it
- Emotion regulation in substance use disorders: a systematic review and meta-analysis.Addiction (Abingdon, England) · 2023Pooled it
- Clearing the smoke: experiences of patients and professionals during a one-year smoking cessation intervention in ambulatory mental healthcare - a qualitative study.Substance abuse treatment, prevention, and policy · 2025Trial
- Neurobehavioral Heterogeneity in Problem Gambling Severity and Nicotine Use Risk: Divergent Profiles of Cognitive and Emotional Control.Journal of gambling studies · 2026Article
- Short-Term Tobacco Abstinence: Effects on Emotional Balance and Psychological Alienation.Healthcare (Basel, Switzerland) · 2025Article
- Effects of psychological conditions and changes on smoking cessation success after a residential smoking cessation therapy program: a retrospective observational study.Journal of Yeungnam medical science · 2025Article
- Interplay Between Health-Promoting Lifestyle, and Cognitive Emotion Regulation with Risk of Cosmetic Surgery Seeking in Young Women.Aesthetic plastic surgery · 2025Article
- Greater resting state functional connectivity of the medial prefrontal cortex with the thalamus, caudate, and putamen in individuals who adhere to the Mediterranean style diets.European journal of nutrition · 2024Article
- How "Light" Is "Light Smoking"? On the Cognitive Power of Nicotine Dependence.Behavioral sciences (Basel, Switzerland) · 2024Article
- Emotion Regulation Difficulties and Smoking Behavior among Adults with Chronic Obstructive Pulmonary Diseases.The Psychiatric quarterly · 2024Article
- Job-related factors associated with tobacco use among Chinese food delivery riders: A cross-sectional survey.Tobacco induced diseases · 2024Article
- Sleep disturbance and suicidality in psychiatrically hospitalized adolescents: The role of specific emotion regulation domains.Journal of clinical psychology · 2023Article
- Cardiac Vagal Control Among Community Cigarette Smokers with Low to Moderate Depressive Symptoms.Applied psychophysiology and biofeedback · 2023Article
- Emotional self-regulation, impulsivity, 5-HTTLPR and tobacco use behavior among psychiatric inpatients.Journal of affective disorders · 2022Article
- Selective D3 receptor antagonism modulates neural response during negative emotional processing in substance dependence.Frontiers in psychiatry · 2022Article
- Developing a Smoking Cessation Intervention for People With Severe Mental Illness Treated by Flexible Assertive Community Treatment Teams in the Netherlands: A Delphi Study.Frontiers in psychiatry · 2022Article
- Relationship between depression, prefrontal creatine and grey matter volume.Journal of psychopharmacology (Oxford, England) · 2021Article
- Difficulties With Executive Function Are Associated With Risky Health Behaviors Among Young Adult Congenital Heart Defect Survivors.The Journal of cardiovascular nursingArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNegative emotional states contribute to cigarette smoking, and difficulties in regulating these states can hinder smoking cessation. Understanding the neural bases of these difficulties in smokers may facilitate development of novel therapies for Tobacco Use Disorder.
methodsThirty-seven participants (18 smokers, 19 nonsmokers; 16-21 years old) completed the Difficulties in Emotion Regulation Scale (DERS), which is comprised of 6 subscales (lack of emotional clarity, lack of emotional awareness, limited access to emotion regulation strategies, nonacceptance of emotional responses, difficulties engaging in goal-directed behaviors, and impulse control difficulties) that combine to provide a total score. Participants also underwent functional magnetic resonance imaging to determine resting-state functional connectivity of the amygdala. Separate ANOVAs were used to determine group differences in self-reports on the DERS. Voxel-wise linear mixed models were performed to determine whether group influenced relationships between whole-brain functional connectivity of the amygdala and scores on the DERS.
resultsCompared with nonsmokers, smokers reported greater difficulties in emotion regulation, denoted by higher total scores on the DERS. Group differences were observed on a subscale of lack of emotional clarity, but no other subscale differences on the DERS were observed. Nonsmokers exhibited a greater negative correlation than smokers between lack of emotional clarity scores and connectivity of the amygdala with the left inferior frontal gyrus. Finally, this amygdala-to-left inferior frontal gyrus connectivity was weaker in smokers than in nonsmokers.
conclusionsThese findings suggest that difficulties in emotion regulation in smokers are at least partially due to lack of emotional clarity. Given the role of the inferior frontal gyrus in understanding emotional states, strengthening connectivity between the amygdala and the inferior frontal gyrus may improve emotional clarity to help smokers regulate their negative emotions, thereby improving their ability to quit smoking.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.