ArticleScientific reports2020
Optic Disc and Macular Vessel Density Measured by Optical Coherence Tomography Angiography in Open-Angle and Angle-Closure Glaucoma.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 31 citations in OpenAlex.
- Applications of optical coherence tomography angiography in glaucoma: current status and future directions.Frontiers in medicine · 2024Review
- Differences and Similarities Between Primary Open Angle Glaucoma and Primary Angle-Closure Glaucoma.Eye and brain · 2024Review
- Current State of Knowledge in Ocular Blood Flow in Glaucoma: A Narrative Review.Clinical ophthalmology (Auckland, N.Z.) · 2023Review
- Structural measurements and vessel density of spectral-domain optic coherence tomography in early, moderate, and severe primary angle-closure glaucoma.International journal of ophthalmology · 2023Article
- Quantitative Measurements of Vessel Density and Blood Flow Areas Primary Angle Closure Diseases: A Study of Optical Coherence Tomography Angiography.Journal of clinical medicine · 2022Article
- Vascular biomarkers from optical coherence tomography angiography and glaucoma: where do we stand in 2021?Acta ophthalmologica · 2022Review
- Spatial positional relationship between macular superficial vessel density and ganglion cell-inner plexiform layer thickness in primary angle closure glaucoma.International ophthalmology · 2022Article
- Comparison of optical coherence tomography angiography metrics in primary angle-closure glaucoma and normal-tension glaucoma.Scientific reports · 2021Article
- Combined wide-field optical coherence tomography angiography density map for high myopic glaucoma detection.Scientific reports · 2021Observational
- Quantification of vascular morphology in optical coherence tomography angiography in primary open angle glaucoma.Advances in ophthalmology practice and researchArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is distinct pathogenesis between primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG). Although elevated intraocular pressure (IOP) is the major risk factor for glaucoma, non-IOP risk factors such as vascular abnormalities and lower systolic/diastolic perfusion pressure may play a role in the pathogenic process. This study aimed to compare the vessel density (VD) in the optic disc and macula using optical coherence tomography angiography (OCTA) between POAG and PACG eyes. Thirty-two POAG eyes, 30 PACG eyes, and 39 control eyes were included. All the optic disc VD parameters except the inside disc VD were significantly lower in glaucomatous eyes than in control eyes. Compared with PACG eyes, only the inferior temporal peripapillary VD was significantly lower in POAG eyes. The parafoveal VD was significantly lower in each quadrant in glaucomatous eyes than in control eyes. The central macular and parafoveal VD did not differ between POAG and PACG eyes. In conclusion, the inferior temporal peripapillary VD was significantly reduced in POAG eyes compared with PACG eyes, while PACG eyes showed a more evenly distributed reduction in the peripapillary VD. The distinct patterns of VD change may be associated with the different pathogenesis between POAG and PACG.
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