ArticleNature communications2020
Modulation of BIN2 kinase activity by HY5 controls hypocotyl elongation in the light.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed, 97 citations in OpenAlex.
- The VvBZR1-VvHY5 Module Integrates Brassinosteroid and Light Signaling to Regulate Anthocyanin Biosynthesis in Grape.Plant, cell & environment · 2026Article
- A BIN2-SOG1 molecular module regulates replication stress response independently on ATR.Science advances · 2026Article
- Molecular mechanisms and breeding strategies for heat tolerance in vegetable crops under global warming.Horticulture research · 2026Article
- Light interacts with mechanical stress to regulate the seed-to-seedling transition.Stress biology · 2025Review
- Split-YFP-coupled interaction-dependent TurboID identifies new functions of basal cell polarity inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Genome-Wide Identification and Analysis of bZIP Transcription Factor Gene Family in Broomcorn Millet (Genes · 2025Article
- Understanding the Brassinosteroid-Dependent Environmental Adaption in Brassicaceae Plants.Plants (Basel, Switzerland) · 2025Review
- Regulatory and retrograde signaling networks in the chlorophyll biosynthetic pathway.Journal of integrative plant biology · 2025Review
- The role of mediator subunit MED7 in Arabidopsis development.Frontiers in plant science · 2025Article
- Physiological and transcriptional analyses of Arabidopsis primary root growth in response to phosphate starvation under light and dark conditions.Frontiers in plant science · 2025Article
- Violet LED light-activated MdHY5 positively regulates phenolic accumulation to inhibit fresh-cut apple fruit browning.Horticulture research · 2025Article
- GhATL68b regulates cotton fiber cell development by ubiquitinating the enzyme required for β-oxidation of polyunsaturated fatty acids.Plant communications · 2024Article
- Circadian Rhythm and Nitrogen Metabolism Participate in the Response of Boron Deficiency in the Root ofInternational journal of molecular sciences · 2024Article
- Functional dissection of phytochrome A in plants.Frontiers in plant science · 2024Review
- The heat response regulators HSFA1s promoteScience advances · 2023Article
- MYB112 connects light and circadian clock signals to promote hypocotyl elongation in Arabidopsis.The Plant cell · 2023Article
- The Chemical Composition and Transcriptome Analysis Reveal the Mechanism of Color Formation in Tea (International journal of molecular sciences · 2023Article
- UV-B promotes flavonoid biosynthesis inHorticulture research · 2023Article
- Article
- Colorful hues: insight into the mechanisms of anthocyanin pigmentation in fruit.Plant physiology · 2023Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ELONGATED HYPOCOTYL 5 (HY5), a basic domain/leucine zipper (bZIP) transcription factor, acts as a master regulator of transcription to promote photomorphogenesis. At present, it's unclear whether HY5 uses additional mechanisms to inhibit hypocotyl elongation. Here, we demonstrate that HY5 enhances the activity of GSK3-like kinase BRASSINOSTEROID-INSENSITIVE 2 (BIN2), a key repressor of brassinosteroid signaling, to repress hypocotyl elongation. We show that HY5 physically interacts with and genetically acts through BIN2 to inhibit hypocotyl elongation. The interaction of HY5 with BIN2 enhances its kinase activity possibly by the promotion of BIN2 Tyr
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.