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ArticleEuropean journal of anaesthesiology2020

Rapid sequence induction: An international survey.

Jozef Klucka, Martina Kosinova, Kai Zacharowski, Stefan De Hert, Milan Kratochvil, Michaela Toukalkova, Roman Stoudek, Hana Zelinkova, Petr Stourac

3 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in European journal of anaesthesiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03694860 completednot on this map

Rapid Sequence Induction in EU: Electronic Survey

TypeobservationalSponsorBrno University HospitalRan2019 to 2019Enrolled1,921ConditionsRapid Sequence InductionArmsquestionnaire
NCT05364801 unknown statusnot on this mapstarted 2022, after this paper: background citation

Impact of Anxiety on the Decision-making Process of Anesthesiologists in the Choice of Drugs for Induction of General Anesthesia of Patients With Aspiration Risk Factors

TypeobservationalSponsorCentre Hospitalier Universitaire de BesanconRan2022 to 2024Enrolled500ConditionsAnxiety, Decision Making, General AnesthesiaArmsSurvey
NCT05775029 active not recruitingnot on this mapstarted 2022, after this paper: background citation

Rapid Sequence Induction Checklist and Its Effect on Compliance to Guidelines and Complications - Follow-up

TypeobservationalSponsorJakob ZeuchnerRan2022 to 2025Enrolled2,300ConditionsRSI, Rapid Sequence Induction, Complication of Anesthesia, Compliant Behavior
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

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  9. SAFE anaesthesia for patients at risk of pulmonary aspiration: A nationwide survey.European journal of anaesthesiology and intensive care · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Jozef KluckaFrom the Department of Paediatric Anaesthesiology and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Jihlavska, Brno, Czech Republic (JK, MKo, MKr, MT, RS, PS), Department of Anaesthesiology, Intensive Care Medicine & Pain Therapy, University Hospital Frankfurt, Frankfurt, Goethe University, Germany (KZ), Department of Anaesthesiology and Peri-operative Medicine, Ghent University Hospital, Ghent University, Ghent, Belgium (SDH) and Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Jihlavska, Brno, Czech Republic (HZ).
Martina Kosinova
Kai Zacharowski
Stefan De Hert
Milan Kratochvil
Michaela Toukalkova
Roman Stoudek
Hana Zelinkova
Petr Stourac
Ghent University Hospital · BEMasaryk University · CZUniversity Hospital Brno · CZUniversity Hospital Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRapid sequence induction (RSI) is a standard procedure, which should be implemented in all patients with a risk of aspiration/regurgitation during anaesthesia induction.

objectiveThe primary aim was to evaluate clinical practice in RSI, both in adult and paediatric populations.

designOnline survey. SETTINGS: A total of 56 countries.

participantsMembers of the European Society of Anaesthesiology.

main outcome measuresThe aim was to identify and describe the actual clinical practice of RSI related to general anaesthesia.

resultsFrom the 1921 respondents, 76.5% (n=1469) were qualified anaesthesiologists. When anaesthetising adults, the majority (61.7%, n=1081) of the respondents preoxygenated patients with 100% O2 for 3 min and 65.9% (n=1155) administered opioids during RSI. The Sellick manoeuvre was used by 38.5% (n=675) and was not used by 37.4% (n=656) of respondents. First-line medications for a haemodynamically stable adult patient were propofol (90.6%, n=1571) and suxamethonium (56.0%, n=932). Manual ventilation (inspiratory pressure <12 cmH2O) was used in 35.5% (n=622) of respondents. In the majority of paediatric patients, 3 min of preoxygenation (56.6%, n=817) and opioids (54.9%, n=797) were administered. The Sellick manoeuvre and manual ventilation (inspiratory pressure <12 cmH2O) in children were used by 23.5% (n=340) and 35.9% (n=517) of respondents, respectively. First-line induction drugs for a haemodynamically stable child were propofol (82.8%, n=1153) and rocuronium (54.7%, n=741).

conclusionWe found significant heterogeneity in the daily clinical practice of RSI. For patient safety, our findings emphasise the need for international RSI guidelines.

trial registrationClinicalTrials.gov identifier: NCT03694860.

Indexed as

Intubation, IntratrachealRapid Sequence Induction and IntubationAdultAnesthesia, GeneralChildHumansSuccinylcholineSurveys and QuestionnairesSuccinylcholine

Identifiers

PMID32221099
PMCPMC7259384
OpenAlexW3013065581

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.