Evidence map›Paper›PMID 32221046›Full record

ArticleAging2020

The association of calcium intake with osteoporotic vertebral fractures in a large Chinese cohort.

Ling Wang, Lu Yin, Xiaoguang Cheng, Kai Li, Yuebo Wang, Yong Zhang, Yang-Yang Duanmu, Xiaoyun Liu, Guijuan Deng, Yang Wang and 4 more

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Ling WangDepartment of Radiology, Beijing Jishuitan Hospital, Beijing 100035, China.
Lu YinMedical Research and Biometrics Center, National Center for Cardiovascular Disease, Beijing 102300, China.
Xiaoguang ChengDepartment of Radiology, Beijing Jishuitan Hospital, Beijing 100035, China.
Kai LiDepartment of Radiology, Beijing Jishuitan Hospital, Beijing 100035, China.
Yuebo WangMedical Research and Biometrics Center, National Center for Cardiovascular Disease, Beijing 102300, China.
Yong ZhangDepartment of Radiology, Beijing Jishuitan Hospital, Beijing 100035, China.
Yang-Yang DuanmuDepartment of Radiology, Beijing Jishuitan Hospital, Beijing 100035, China.
Xiaoyun LiuMedical Research and Biometrics Center, National Center for Cardiovascular Disease, Beijing 102300, China.
Guijuan DengMedical Research and Biometrics Center, National Center for Cardiovascular Disease, Beijing 102300, China.
Yang WangMedical Research and Biometrics Center, National Center for Cardiovascular Disease, Beijing 102300, China.
Nicola VeroneseAging Branch (N.V.), National Research Council, Neuroscience Institute, Padova, Italy.
Wei LiMedical Research and Biometrics Center, National Center for Cardiovascular Disease, Beijing 102300, China.
Wei TianDepartment of Spine Surgery, Beijing Jishuitan Hospital, Beijing 100035, China.
PURE China CASH study team
Peking University · CNNeuroscience Institute · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of calcium on prevention of osteoporosis and related fracture which are aging issues is unclear. The aim of this study is to explore the association of calcium intake with vertebral fracture. This study enrolled 3,457 participants from China Action on Spine and Hip Status (CASH) study from 2013 and 2017. Dietary calcium intake was collected using validated food frequency questionnaires (FFQ). Vertebral fracture of CT images was defined as the primary outcome. The mean calcium intake of men and women were 522.75mg/day and 507.21mg/day, respectively. 6% reduction in the odds of fracture risk was observed per 100 unit increase of calcium intake from food among females (OR, 0.94; 95% CI, 0.89-0.99), but results among males were not significant. We divided calcium intake into quintiles when modelling its associations with fracture risk, negative associations of fracture risk with calcium intake were found among females. In a population with low usual calcium intake, higher dietary calcium intake was associated with fewer vertebral fracture in women and that no such association was seen in men.

Indexed as

AgedAsian PeopleBone DensityBone Density Conservation AgentsCalciumCalcium, DietaryChinaCohort StudiesFemaleHumansMaleMiddle AgedOsteoporosisOsteoporotic FracturesProspective StudiesRisk FactorsBone Density Conservation AgentsCalciumCalcium, Dietarycalcium intakeQCTvertebral fracture

Identifiers

PMID32221046
PMCPMC7138559
OpenAlexW3013802436

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.