ArticleCurrent biology : CB2020
Layer-Specific Contributions to Imagined and Executed Hand Movements in Human Primary Motor Cortex.
Article in Current biology : CB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed, 68 citations in OpenAlex.
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- Bridging the gap with invasive imaging: promises and challenges of a new generation of ultrahigh resolution fMRI.bioRxiv : the preprint server for biology · 2026Article
- TMS-Based Neurofeedback Training of Mental Finger Individuation Induces Neuroplastic Changes in the Sensorimotor System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Motor imagery enhances performance beyond the imagined action.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Hippocampal-entorhinal cognitive maps and cortical motor system represent action plans and their outcomes.Nature communications · 2025Article
- The Effects of Motor Imagery on Trapeziometacarpal Osteoarthritis in Women During the Post-Surgical Immobilization Period: A Randomized Clinical Trial.Healthcare (Basel, Switzerland) · 2025Article
- The laminar pattern of proprioceptive activation in human primary motor cortex.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- How Layer-Specific fMRI Can Contribute to Understanding Perceptual Disturbances Across Psychiatric Disorders.Current topics in behavioral neurosciences · 2025Review
- Revealing layer-specific cortical activity in human M1 using high-resolution line-scanning fMRI.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Blood nulling versus tissue suppression: Enhancing integrated VASO and perfusion (VAPER) contrast for laminar fMRI.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- EEG decoding with spatiotemporal convolutional neural network for visualization and closed-loop control of sensorimotor activities: A simultaneous EEG-fMRI study.Human brain mapping · 2024Article
- Characterisation of laminar and vascular spatiotemporal dynamics of CBV and BOLD signals using VASO and ME-GRE at 7T in humans.bioRxiv : the preprint server for biology · 2024Article
- Characterisation of laminar and vascular spatiotemporal dynamics of CBV and BOLD signals using VASO and ME-GRE at 7T in humans.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Exploring methodological frontiers in laminar fMRI.Psychoradiology · 2024Review
- Supramodality does not specify the nature of conceptual representations.Language, cognition and neuroscience · 2024Article
- Review
- Brain activity associated with taste stimulation: A mechanism for neuroplastic change?Brain and behavior · 2023Article
- Motor imagery has a priming effect on motor execution in people with multiple sclerosis.Frontiers in human neuroscience · 2023Article
- Morphological Features of Human Dendritic Spines.Advances in neurobiology · 2023Review
- Evaluating the capabilities and challenges of layer-fMRI VASO at 3T.Aperture neuro · 2023Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
The human ability to imagine motor actions without executing them (i.e., motor imagery) is crucial to a number of cognitive functions, including motor planning and learning, and has been shown to improve response times and accuracy of subsequent motor actions [1, 2]. Although these behavioral findings suggest the possibility that imagined movements directly influence primary motor cortex (M1), how this might occur remains unknown [3]. Here, we use a non-blood-oxygen-level-dependent (BOLD) method for collecting fMRI data, called vascular space occupancy (VASO) [4, 5], to measure neural activations across cortical laminae in M1 while participants either tapped their thumb and forefinger together or simply imagined doing so. We report that, whereas executed movements (i.e., finger tapping) evoked neural responses in both the superficial layers of M1 that receive cortical input and the deep layers of M1 that send output to the spinal cord to support movement, imagined movements evoked responses in superficial cortical layers only. Furthermore, we found that finger tapping preceded by both imagined and executed movements showed a reduced response in the superficial layers (repetition suppression) coupled with a heightened response in the deep layers (repetition enhancement). Taken together, our results provide evidence for a mechanism whereby imagined movements can directly affect motor performance and might explain how neural repetition effects lead to improvements in behavior (e.g., repetition priming).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.