ArticleBMC plant biology2020
Transcriptomic and metabolomic analysis provides insights into anthocyanin and procyanidin accumulation in pear.
Article in BMC plant biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 76 citations in OpenAlex.
- Metabolomic analysis reveals flavonoid accumulation patterns in four apricot cultivars.Food chemistry: X · 2026Article
- Anthocyanin accumulation in fruit crops: a multi-layered regulatory network integrating molecular, epigenetic, hormonal and environmental regulation.Molecular biology reports · 2026Review
- The Genome-Wide Identification of the GST Gene Family and Functional Characterization ofBiology · 2026Article
- Analysis of Differences in Metabolite Composition and Bioactivity of Black Mulberry Fruits from Four Production Regions in Xinjiang.Foods (Basel, Switzerland) · 2026Article
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- The genomic design of fruit metabolomes.Plant communications · 2025Review
- Metabolic Pathways and Molecular Regulatory Mechanisms of Fruit Color Change During Greening Stage of Peppers (International journal of molecular sciences · 2025Article
- BrGSTF12, an anthocyanin-related glutathione S-transferase gene, is essential for light-induced anthocyanin accumulation in zicaitai (Brassica Rapa Var. purpuraria).BMC plant biology · 2025Article
- Flavonoids profile and antioxidant capacity of four wine grape cultivars and their wines grown in the Turpan Basin of China, the hottest wine region in the world.Food chemistry: X · 2025Article
- Metabolomic and transcriptomic analyses provide insights into the red pigmentation in loquat (Frontiers in plant science · 2025Article
- VvWRKY5 positively regulates wounding-induced anthocyanin accumulation in grape by interplaying with VvMYBA1 and promoting jasmonic acid biosynthesis.Horticulture research · 2024Article
- Genome-Wide Identification ofInternational journal of molecular sciences · 2024Article
- Feruloyl Glyceride Mitigates Tomato Postharvest Rot by InhibitingFoods (Basel, Switzerland) · 2024Article
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- VvWRKY5 enhances white rot resistance in grape by promoting the jasmonic acid pathway.Horticulture research · 2023Article
- Genome assembly and resequencing analyses provide new insights into the evolution, domestication and ornamental traits of crape myrtle.Horticulture research · 2023Article
- Persulfidation of transcription factor MYB10 inhibits anthocyanin synthesis in red-skinned pear.Plant physiology · 2023Article
- A Review of Classification, Biosynthesis, Biological Activities and Potential Applications of Flavonoids.Molecules (Basel, Switzerland) · 2023Review
- The complexities of proanthocyanidin biosynthesis and its regulation in plants.Plant communications · 2023Review
- Transcriptomic and metabolomic data reveal key genes that are involved in the phenylpropanoid pathway and regulate the floral fragrance of Rhododendron fortunei.BMC plant biology · 2023Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPear is one of the most important fruit crops worldwide. Anthocyanins and procyanidins (PAs) are important secondary metabolites that affect the appearance and nutritive quality of pear. However, few studies have focused on the molecular mechanism underlying anthocyanin and PA accumulation in pear.
resultsWe conducted metabolome and transcriptome analyses to identify candidate genes involved in anthocyanin and PA accumulation in young fruits of the pear cultivar 'Clapp Favorite' (CF) and its red mutation cultivar 'Red Clapp Favorite' (RCF). Gene-metabolite correlation analyses revealed a 'core set' of 20 genes that were strongly correlated with 10 anthocyanin and seven PA metabolites. Of these, PcGSTF12 was confirmed to be involved in anthocyanin and PA accumulation by complementation of the tt19-7 Arabidopsis mutant. Interestingly, PcGSTF12 was found to be responsible for the accumulation of procyanidin A3, but not petunidin 3, 5-diglucoside, opposite to the function of AtGSTs in Arabidopsis. Transformation with PcGSTF12 greatly promoted or repressed genes involved in anthocyanin and PA biosynthesis, regulation, and transport. Electrophoretic mobility shift and luciferase reporter assays confirmed positive regulation of PcGSTF12 by PcMYB114.
conclusionThese findings identify a core set of genes for anthocyanin and PA accumulation in pear. Of these, PcGSTF12, was confirmed to be involved in anthocyanin and PA accumulation. Our results also identified an important anthocyanin and PA regulation node comprising two core genes, PcGSTF12 and PcMYB114. These results provide novel insights into anthocyanin and PA accumulation in pear and represent a valuable data set to guide future functional studies and pear breeding.
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