ArticleESC heart failure2020
Right ventricular mechanical pattern in patients undergoing mitral valve surgery: a predictor of post-operative dysfunction?
Article in ESC heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05620992 (Evaluation of Right Ventricular Function Post Mitral Valve Operations in Patients With Pulmonary Hypertension.), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Right Ventricular Function Post Mitral Valve Operations in Patients With Pulmonary Hypertension.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- The predictive value of right ventricle speckle tracking echocardiography in patients undergoing cardiac surgery, a systematic review and meta-analysis.Cardiovascular ultrasound · 2025Pooled it
- Echocardiographic Estimation of right ventricular stroke work index based on pulmonary regurgitant velocity in heart failure with reduced ejection fraction.Journal of echocardiography · 2026Article
- Predicting adverse outcomes after cardiac surgery and structural interventions: the role of right ventricular function.Future cardiology · 2026Review
- 3D echo derived right ventricular principal surface strain in pulmonary arterial hypertension.American journal of physiology. Heart and circulatory physiology · 2026Article
- Artificial Intelligence-Enabled Echocardiographic Assessment of Right Ventricular Function.medRxiv : the preprint server for health sciences · 2026Article
- Challenges and opportunities in assessing right ventricular structure and function: a Roadmap for standardization, clinical implementation and research.Nature reviews. Cardiology · 2026Review
- Evolution of right ventricular contraction patterns of adult heart transplant recipients by three-dimensional echocardiography.Frontiers in cardiovascular medicine · 2026Article
- Employment of artificial intelligence for an unbiased evaluation regarding the recovery of right ventricular function after mitral valve transcatheter edge-to-edge repair.European journal of heart failure · 2025Article
- 3D Echocardiographic Assessment of Right Ventricular Involvement of Left Ventricular Hypertrabecularization from a New Perspective.Journal of imaging · 2025Article
- Impact of the right ventricular mechanical pattern assessed by three-dimensional echocardiography on adverse outcomes following cardiac surgery.Scientific reports · 2025Article
- Prognostic Value of Pre-Operative Transthoracic Echocardiography in Patients with Primary Mitral Regurgitation.Reviews in cardiovascular medicine · 2024Review
- The effects of mitral stenosis on right ventricular mechanics assessed by three-dimensional echocardiography.Scientific reports · 2024Article
- Transcatheter Mitral Valve Intervention: Current and Future Role of Multimodality Imaging for Device Selection and Periprocedural Guidance.Medicina (Kaunas, Lithuania) · 2024Review
- Right Ventricular Structure and Function in Adolescent Athletes: A 3D Echocardiographic Study.International journal of sports medicine · 2024Article
- Right Ventricular Dysfunction before and after Cardiac Surgery: Prognostic Implications.Journal of clinical medicine · 2024Review
- Cardiac reverse remodeling in primary mitral regurgitation: mitral valve replacement vs. mitral valve repair.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Article
- Editorial: Added value of 3D imaging in the diagnosis and prognostication of patients with right ventricular dysfunction.Frontiers in cardiovascular medicine · 2023Article
- Added value of 3D echocardiography in the diagnosis and prognostication of patients with right ventricular dysfunction.Frontiers in cardiovascular medicine · 2023Review
- There is more than just longitudinal strain: Prognostic significance of biventricular circumferential mechanics.Frontiers in cardiovascular medicine · 2023Article
- Right ventricular volume-strain loops using 3D echocardiography-derived mesh models: proof-of-concept application on patients undergoing different types of open-heart surgery.Quantitative imaging in medicine and surgery · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 2 countries.
Funding
Abstract
aimsThe PREPARE-MVR study (PRediction of Early PostoperAtive Right vEntricular failure in Mitral Valve Replacement/Repair patients) sought to investigate the alterations of right ventricular (RV) contraction pattern in patients undergoing mitral valve replacement/repair (MVR) and to explore the associations between pre-operative RV mechanics and early post-operative RV dysfunction (RVD). METHODS AND
resultsWe prospectively enrolled 42 patients (63 ± 11 years, 69% men) undergoing open-heart MVR. Transthoracic three-dimensional (3D) echocardiography was performed pre-operatively, at intensive care unit discharge, and 6 months after surgery. The 3D model of the RV was reconstructed, and RV ejection fraction (RVEF) was calculated. We decomposed the motion of the ventricle to compute longitudinal ejection fraction (LEF) and radial ejection fraction (REF). Pulmonary artery catheterization was performed to monitor RV stroke work index (RVSWi). RVEF was slightly decreased after MVR [52 (50-55) vs. 51 (46-54)%; P = 0.001], whereas RV contraction pattern changed notably. Before MVR, the longitudinal shortening was the main contributor to global systolic RV function [LEF/RVEF vs. REF/RVEF; 0.53 (0.47-0.58) vs. 0.33 (0.22-0.42); P < 0.001]. Post-operatively, the radial motion became dominant [0.33 (0.28-0.43) vs. 0.46 (0.37-0.51); P = 0.004]. However, this shift was temporary as 6 months later the two components contributed equally to global RV function [0.44 (0.38-0.50) vs. 0.41 (0.36-0.49); P = 0.775]. Pre-operative LEF was an independent predictor of post-operative RVD defined as RVSWi < 300 mmHg⋅mL/m
conclusionsMVR induces a significant shift in the RV mechanical pattern. Advanced indices of RV mechanics are associated with invasively measured parameters of RV contractility and may predict post-operative RVD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.