ArticleInternational wound journal2020
Multiple preoperative biomarkers are associated with incidence of surgical site infection following surgeries of ankle fractures.
Article in International wound journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Explainable Machine Learning Predictive Models for Surgical Site Infections: Scoping Review.Journal of medical Internet research · 2026Article
- Identification and treatment results for fracture-related infections following operative repair of a rotational ankle fractures.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Post-operative infection following ankle fracture surgery: a current concepts review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Review
- Article
- Adverse effect of smoking on surgical site infection following ankle and calcaneal fracture fixation: a meta-analysis.EFORT open reviews · 2024Article
- Wound complication risk factors following open reduction and internal fixation of ankle fractures.International wound journal · 2024Article
- Incidence and Risk Factors for Surgical Site Infection in Ankle Fractures: An Observational Study of 480 Patients in Sweden.Journal of clinical medicine · 2023Article
- Trends and Risk Factors for Surgical Site Infection after Treatment of the Ankle Fracture: National Cohort Study.Journal of clinical medicine · 2023Article
- Development of a nomogram to predict surgical site infection after open reduction and internal fixation for closed pilon fracture: a prospective single-center study.Journal of orthopaedic surgery and research · 2023Article
- Risk factors for deep surgical site infection following surgically treated peri-ankle fractures: a case-control study based on propensity score matching.Journal of orthopaedic surgery and research · 2022Article
- Relationship between surgeon volume and the risk of deep surgical site infection (DSSI) following open reduction and internal fixation of displaced intra-articular calcaneal fracture.International wound journal · 2022Article
- Surgeon volume and the risk of deep surgical site infection following open reduction and internal fixation of closed tibial plateau fracture.International orthopaedics · 2022Article
- Article
- Multiple preoperative biomarkers are associated with incidence of surgical site infection following surgeries of ankle fractures.International wound journal · 2020Article
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Authors and funding
6 authors.
Funding
Abstract
The aim of the study was to investigate the epidemiologic characteristics of surgical site infection (SSI) following surgeries of ankle fractures. This was a retrospective study. Patients who underwent surgeries for ankle fractures in our hospital between January 2016 and June 2019 were included. Inpatient medical records were inquired for data collection, including demographics, comorbidities, injury-related data, laboratory biomarkers, and confirmation of the SSI cases. Univariate analyses and multivariate logistic regression analyses were used to identify the independent risk factors. Among the 1532 patients, 45 had a postoperative SSI, indicating the incidence rate of 2.9%. About 18% of SSIs were identified after discharge. Twenty percent of SSIs were caused by mixed bacteria, and 39% were caused by drug-resistant bacteria. In the final multivariate model, 7 factors including 5 biomarkers were identified to be independently associated with SSI: gender (male vs female, OR, 2.69; 95% CI, 1.33-4.76), perioperative blood transfusion (OR. 3.02; 95% CI, 1.30-7.04), albumin <35 g/L (OR, 2.87; 95% CI, 1.31-6.31), lower high-density lipoprotein cholesterol (HDL-C) (OR, 2.34; 95% CI, 1.19-4.60), haemoglobin (OR, 2.16; 95% CI, 1.03-4.67), elevated alanine aminotransferase (OR, 2.09; 95% CI, 1.10-3.95) and neutrophile/lymphocyte rate (NLR, OR, 3.45; 95% CI, 1.33-6.74). These epidemiologic data on SSI may help counsel patients about the risk of SSI, individualised assessment of the risk factors, and accordingly the risk stratification.
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