Observational studyInternational wound journal2020
Effect of lower extremity amputation on caregiving burden in caregivers of patients with diabetic foot: Prospective cohort study.
Observational study in International wound journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Outcomes following major dysvascular lower limb amputation: an updated systematic review.BMC cardiovascular disorders · 2026Pooled it
- Diabetes-related foot complications and caregiver burden: insights from a cross-sectional study in multi-ethnic Asians.Journal of global health · 2026Article
- Financial and functional outcomes in diabetes-related foot disease patients undergoing major lower limb amputation: An observational pilot study from LMIC.Pakistan journal of medical sciences · 2026Article
- Intangible cost and its associated factors among caregivers of individuals with Type 2 Diabetes Mellitus managed at primary healthcare settings: a scoping review.BMC health services research · 2025Article
- Burden of caregivers of diabetic foot ulcers: a single-centre, descriptive correlational study in Türkiye.BMJ open · 2025Article
- Hyperbaric Oxygen Therapy as an Effective Adjunctive Treatment in the Reconstruction of Tissue Defects With Graft in Diabetic Foot Patients: A Retrospective Cohort Study.International wound journal · 2025Article
- Lower-Limb Amputees and Family Caregivers: Challenges, Needs, and Strategies for Empowerment-A Qualitative Study.Nursing reports (Pavia, Italy) · 2025Article
- Outcome of diabetic foot ulcers at a Tertiary Care Foot Centre in Pakistan.International wound journal · 2025Article
- "After Cutting It, Things Have Never Remained the Same": A Qualitative Study of the Perspectives of Amputees and Their Caregivers.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Experiences and challenges of family caregivers of people with lower limb amputation: a qualitative study.Revista da Escola de Enfermagem da U S P · 2025Article
- Epidemiology and Burden of Peripheral Artery Disease in People With Type 2 Diabetes: A Systematic Literature Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024Review
- The efficacy of custom-made offloading devices for diabetic foot ulcer prevention: a systematic review.Diabetology & metabolic syndrome · 2024Review
- Needs of Family Caregivers of People with Lower Limb Amputations: A Scoping Review.Behavioral sciences (Basel, Switzerland) · 2024Article
- Mobilizing morality: how caregivers in Vietnam handle the challenges of daily diabetes care.BMC public health · 2023Article
- The state of cancer research in fragile and conflict-affected settings in the Middle East and North Africa Region: A bibliometric analysis.Frontiers in oncology · 2023Article
- Thoughts and experiences on leg amputation among patients with diabetic foot ulcers.International journal of qualitative studies on health and well-being · 2022Article
- Trends of limb amputation considering type, level, sex and age in Saskatchewan, Canada 2006-2019: an in-depth assessment.Archives of public health = Archives belges de sante publique · 2022Article
- Effect of lower extremity amputation on caregiving burden in caregivers of patients with diabetic foot: Prospective cohort study.International wound journal · 2020Observational
- The Influence of 6-Month Interdisciplinary Accompaniment on Family Caregivers' Knowledge and Self-Efficacy Regarding Diabetic Wound Care.SAGE open nursingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lower extremity amputation as a treatment of diabetic foot ulcer is probably a major burden for the patient's family and friends, who typically act as caregivers and support the patient in coping with the physical disabilities and emotional distress. In the present prospective study, we investigated the effects of different lower extremity amputation levels for diabetic foot ulcer treatment on caregivers of patients with diabetes using the Zarit Burden Interview (ZBI-12) scale. Patients with diabetic foot ulcers who underwent unilateral major amputation (above-below knee) and minor amputation of foot (heel sparing) and their caregivers were requested to volunteer to participate in this study from June 2016 to December 2018. The ZBI-12 form was completed immediately preoperatively and 3 and 6 months after postoperatively. In the minor amputation group, the mean age of the 51 patients was 72.1 years. In the major amputation group, the mean age of the 88 patients was 73.7 years. Both groups of caregivers of patients with minor amputation and major amputations showed a significant improvement in ZBI-12 score when compared preoperatively and at 3- and 6-month follow-up visits. The mean ZBI-12 score was significantly higher in the major than in the minor amputation group in preoperative and all postoperative visits. The absence of the ankle joint in the below- or above-knee amputation renders it more difficult for the amputee to quickly learn the use of prosthesis, thereby increasing the burden of the patient and caregivers. We found that lower extremity amputation for the treatment of chronic diabetic foot ulcers has significantly favourable effect on the caregiver burden, and thereby heel sparing was considerably more effective for the caregiver burden.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.