ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020
Evaluation of quality of life and its influencing factors after transplantation of leukemia patients based on SF-36 score: a cohort study.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- The experience of fertility preservation decision-making in hematopoietic stem cell transplantation patients: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Trajectories of quality of life during hematopoietic stem cell transplantation: longitudinal cohort study.Scientific reports · 2025Article
- Relationship between work performance and quality of life in long-term survivors of pediatric and adolescent hematopoietic cell transplant.Journal of cancer survivorship : research and practice · 2024Article
- Quality of life among family caregivers of cancer patients: an investigation of SF-36 domains.BMC psychology · 2023Article
- Stress Estimation Using Biometric and Activity Indicators to Improve QoL of the Elderly.Sensors (Basel, Switzerland) · 2023Article
- Long-term survivors demonstrate superior quality of life after haploidentical stem cell transplantation to matched sibling donor transplantation.Journal of translational medicine · 2022Article
- Prevalence and Determinants of Return to Work as a Patient-Centered Outcome in Survivors of Hematopoietic Cell Transplantation.Current hematologic malignancy reports · 2022Review
- Health-Related Quality of Life (HRQoL) of People over 65 Years of Age.International journal of environmental research and public health · 2022Article
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Authors and funding
13 authors.
Funding
Abstract
purposeThe aim of this study is to clarify the short-term quality of life (QoL) of acute leukemia (AL) patients early after stem cell transplantation (SCT) and related predictors of QoL recovery.
methodsWe investigated adult AL patients who underwent SCT at the Institute of Hematology and Blood Diseases Hospital after transplantation. Physical/functional and emotional/mental recovery were evaluated using the Short Form 36 (SF-36) questionnaire to identify its trajectory as well as related predictors for the physical component summary (PCS) and mental component summary (MCS). The score was also used to establish a QoL prediction model.
resultsA total of 326 AL patients responded to our QoL survey. The results revealed the profile of patient follow-up from 2013 to 2015. Along follow-up after transplantation, there was a significant increase in PCS (p = 0.139) and MCS (p = 0.122). On multivariate regression analysis, apart from follow-up, marriage, financial situation, employment situation, and history of chronic graft-versus-host disease (cGVHD) had clinical significance for both PCS and MCS. A prediction model for patient risk hierarchy estimation was further established. The logistic results revealed that the significant characteristics of patients with high PCS and high MCS were unmarried, without financial burden, reliable on drugs, and with history of acute graft-versus-host disease (aGVHD).
conclusionsThis well-established study enabled evaluation of the QoL of AL patients post-HSCT in China. The established prediction model could provide more indications and insights into improvement in quality of life for better medical interventions.
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