Evidence map›Paper›PMID 32219216›Full record

ArticleACS pharmacology & translational science2019

Calcitonin-Receptor-Like Receptor Signaling Governs Intestinal Lymphatic Innervation and Lipid Uptake.

Reema B Davis, Shengli Ding, Natalie R Nielsen, John B Pawlak, Elizabeth S Blakeney, Kathleen M Caron

Open access · greenAbstract read
In one paragraph

Article in ACS pharmacology & translational science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Buttons and Zippers: Endothelial Junctions in Lymphatic Vessels.Cold Spring Harbor perspectives in medicine · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Dawn of a New RAMPage.Trends in pharmacological sciences · 2020
    Review
  13. Molecular Mechanisms Controlling Lymphatic Endothelial Junction Integrity.Frontiers in cell and developmental biology · 2020
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Reema B DavisDepartment of Cell Biology and Physiology, University of North Carolina Chapel Hill, 111 Mason Farm Road, 6312B Medical Biomolecular Research Building, CB#7545, Chapel Hill, North Carolina 27599-7545, United States.
Shengli DingDepartment of Cell Biology and Physiology, University of North Carolina Chapel Hill, 111 Mason Farm Road, 6312B Medical Biomolecular Research Building, CB#7545, Chapel Hill, North Carolina 27599-7545, United States.
Natalie R NielsenDepartment of Cell Biology and Physiology, University of North Carolina Chapel Hill, 111 Mason Farm Road, 6312B Medical Biomolecular Research Building, CB#7545, Chapel Hill, North Carolina 27599-7545, United States.
John B PawlakDepartment of Cell Biology and Physiology, University of North Carolina Chapel Hill, 111 Mason Farm Road, 6312B Medical Biomolecular Research Building, CB#7545, Chapel Hill, North Carolina 27599-7545, United States.
Elizabeth S BlakeneyDepartment of Cell Biology and Physiology, University of North Carolina Chapel Hill, 111 Mason Farm Road, 6312B Medical Biomolecular Research Building, CB#7545, Chapel Hill, North Carolina 27599-7545, United States.
Kathleen M CaronDepartment of Cell Biology and Physiology, University of North Carolina Chapel Hill, 111 Mason Farm Road, 6312B Medical Biomolecular Research Building, CB#7545, Chapel Hill, North Carolina 27599-7545, United States.
University of North Carolina at Chapel Hill · US

Funding

Adrenomedullin Signaling at the Maternal-Fetal InterfaceR01HD060860 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Kathleen M Caron · 2009 to 2026
$4.8M
Cardiac Lymphatics in Heart FailureR01HL129086 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CARON, KATHLEEN M · 2016 to 2023
$4.1M
GPCR-mediated pathways for regulation of intestinal lymphatic functionR01DK119145 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CARON, KATHLEEN M · 2019 to 2023
$2.6M
Causes and Consequences of Digestive Tract LymphangiectasiaR01DK099156 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CARON, KATHLEEN M · 2013 to 2016
$1.3M
NHLBI NIH HHS R01 HL129086NICHD NIH HHS R01 HD060860NIDDK NIH HHS R01 DK099156NIDDK NIH HHS R01 DK119145
6 · The paper itself

Abstract

The absorption of dietary fat requires complex neuroendocrine-mediated regulation of chylomicron trafficking through enterocytes and intestinal lymphatic vessels. Calcitonin-receptor-like receptor (

Identifiers

PMID32219216
PMCPMC7088972
OpenAlexW2911731251

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.