Evidence map›Paper›PMID 32219167›Full record

ArticleScience advances2020

Two different epigenetic information channels in wild three-spined sticklebacks are involved in salinity adaptation.

Melanie J Heckwolf, Britta S Meyer, Robert Häsler, Marc P Höppner, Christophe Eizaguirre, Thorsten B H Reusch

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 153 citations in OpenAlex.

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  10. Complementary genetic and epigenetic changes facilitate rapid adaptation to multiple global change stressors.Proceedings of the National Academy of Sciences of the United States of America · 2025
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Melanie J HeckwolfMarine Evolutionary Ecology, GEOMAR Helmholtz Centre for Ocean Research Kiel, Kiel, Germany.ORCID 0000-0002-7507-8895
Britta S MeyerMarine Evolutionary Ecology, GEOMAR Helmholtz Centre for Ocean Research Kiel, Kiel, Germany.ORCID 0000-0002-2549-1825
Robert HäslerInstitute of Clinical Molecular Biology, Kiel University, Kiel, Germany.ORCID 0000-0003-4174-8229
Marc P HöppnerInstitute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
Christophe EizaguirreSchool of Biological and Chemical Sciences, Queen Mary University of London, London, UK.
Thorsten B H ReuschMarine Evolutionary Ecology, GEOMAR Helmholtz Centre for Ocean Research Kiel, Kiel, Germany.ORCID 0000-0002-8961-4337
GEOMAR Helmholtz Centre for Ocean Research Kiel · DEChristian-Albrechts-Universität zu Kiel · DEQueen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epigenetic inheritance has been proposed to contribute to adaptation and acclimation via two information channels: (i) inducible epigenetic marks that enable transgenerational plasticity and (ii) noninducible epigenetic marks resulting from random epimutations shaped by selection. We studied both postulated channels by sequencing methylomes and genomes of Baltic three-spined sticklebacks (

Indexed as

AcclimatizationAdaptation, BiologicalEpigenesis, GeneticSalinityAnimalsComputational BiologyCpG IslandsDNA MethylationEpigenomicsGene Expression RegulationGene OntologyGenomeGenomicsSmegmamorpha

Identifiers

PMID32219167
PMCPMC7083608
OpenAlexW3012350583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.