Evidence map›Paper›PMID 32219016›Full record

ArticlePeerJ2020

Discovery of potential targets of Triptolide through inverse docking in ovarian cancer cells.

Qinhang Wu, Gang Bao, Yang Pan, Xiaoqi Qian, Furong Gao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Qinhang WuDepartment of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Gang BaoDepartment of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Yang PanDepartment of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Xiaoqi QianDepartment of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Furong GaoDepartment of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Nanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triptolide (TPL) is proposed as an effective anticancer agent known for its anti-proliferation of a variety of cancer cells including ovarian cancer cells. Although some studies have been conducted, the mechanism by which TPL acts on ovarian cancer remains to be clearly described. Herein, systematic work based on bioinformatics was carried out to discover the potential targets of TPL in SKOV-3 cells. TPL induces the early apoptosis of SKOV-3 cells in a dose- and time-dependent manner with an IC

Indexed as

Inverse dockingOvarian cancerPotential targetsSKOV-3 cellTriptolide

Identifiers

PMID32219016
PMCPMC7085293
OpenAlexW3011027185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.