Evidence map›Paper›PMID 32218855›Full record

ArticleOncology letters2020

NOS1 expression promotes proliferation and invasion and enhances chemoresistance in ovarian cancer.

Zhiwei Zou, Xiaoxuan Li, Yongliang Sun, Linlin Li, Qianbing Zhang, Lingqun Zhu, Zhuo Zhong, Meng Wang, Qianli Wang, Zhenjun Liu and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Molecular mechanisms associated with chemoresistance in esophageal cancer.Cellular and molecular life sciences : CMLS · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Zhiwei ZouCancer Research Institute, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Xiaoxuan LiDepartment of Obstetrics and Gynecology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, P.R. China.
Yongliang SunCancer Research Institute, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Linlin LiCancer Research Institute, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Qianbing ZhangCancer Research Institute, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Lingqun ZhuCancer Research Institute, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Zhuo ZhongCancer Research Institute, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Meng WangCancer Research Institute, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Qianli WangCancer Research Institute, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Zhenjun LiuDepartment of Vascular Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Yifeng WangDepartment of Obstetrics and Gynecology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, P.R. China.
Yifang PingInstitute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University, Chongqing, Sichuan 400038, P.R. China.
Kaitai YaoCancer Research Institute, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Bingtao HaoCancer Research Institute, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Qiuzhen LiuCancer Research Institute, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Southern Medical University · CNNanfang Hospital · CNSouthwest Hospital · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitric oxide (NO), an important chemical messenger, serves a dual role in tumor progression. Nitric oxide synthase isoform 1 (NOS1) was observed to be increasingly expressed in various types of cancer, and its expression has been associated with tumor progression. However, the level of NOS1 expression and the associated functions of NOS1 in human ovarian cancer remain undefined. Using gene expression profiles of ovarian cancer from the Gene Expression Omnibus (GEO) database, the present study revealed that NOS1 was increasingly expressed in ovarian cancer tissues. The present study investigated the level of NOS1 expression and its effects on

Indexed as

chemoresistanceinvasionmigrationnitric oxide synthase isoform 1ovarian cancerproliferation

Identifiers

PMID32218855
PMCPMC7068236
OpenAlexW3003328884

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.