Evidence map›Paper›PMID 32218851›Full record

ArticleOncology letters2020

Complex karyotype with cryptic

Moneeb A K Othman, Marina Đurišić, Gordana Samardzija, Dragana Vujić, Nina Lakic, Zeljko Zecevic, Fawaz Al-Shaheri, Rouben Aroutiounian, Joana B Melo, Isabel M Carreira and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. IKZF1Pediatric blood & cancer · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Moneeb A K OthmanJena University Hospital, Friedrich Schiller University, Institute of Human Genetics, D-07747 Jena, Germany.
Marina ĐurišićMother and Child Health Care Institute of Serbia 'Dr Vukan Cupic', 11070 Belgrade, Serbia.
Gordana SamardzijaMother and Child Health Care Institute of Serbia 'Dr Vukan Cupic', 11070 Belgrade, Serbia.
Dragana VujićMedical School, University of Belgrade, 11000 Belgrade, Serbia.
Nina LakicMother and Child Health Care Institute of Serbia 'Dr Vukan Cupic', 11070 Belgrade, Serbia.
Zeljko ZecevicMother and Child Health Care Institute of Serbia 'Dr Vukan Cupic', 11070 Belgrade, Serbia.
Fawaz Al-ShaheriJena University Hospital, Friedrich Schiller University, Institute of Human Genetics, D-07747 Jena, Germany.
Rouben AroutiounianDepartment of Genetics and Cytology, Yerevan State University, 0025 Yerevan, Armenia.
Joana B MeloLaboratory of Cytogenetics and Genomics, Faculty of Medicine, University of Coimbra, 3000-354 Coimbra, Portugal.
Isabel M CarreiraLaboratory of Cytogenetics and Genomics, Faculty of Medicine, University of Coimbra, 3000-354 Coimbra, Portugal.
Britta MeyerZytoVision, D-27572 Bremerhaven, Germany.
Thomas LiehrJena University Hospital, Friedrich Schiller University, Institute of Human Genetics, D-07747 Jena, Germany.
Institute of Public Health of Serbia · RSFriedrich Schiller University Jena · DEUniversity of Coimbra · PTUniversity of Belgrade · RSYerevan State University · AM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

B-cell acute lymphoblastic leukemia (B-ALL) is a hematopoietic malignancy characterized by overproduction of immature B-lymphoblasts. B-ALL is the most common pediatric tumor and remains the leading cause of mortality in children and adolescents. Molecular and cytogenetic analyses of B-ALL revealed recurrent genetic and structural genomic alterations which are routinely applied for diagnosis, prognosis and choice of treatment regimen. The present case report describes a 4-year-old female diagnosed with B-ALL. GTG-banding at low resolution revealed an abnormal clone with 46,XX,?t(X;19)(q13;q13.3),der(9) besides normal cells. Molecular cytogenetics demonstrated a balanced translocation between chromosomes 16 and 19, and an unbalanced translocation involving chromosomes 5 and 9. A locus-specific probe additionally identified that the

Indexed as

array-comparative genomic hybridizationCDKN2A/Bchildhood B-cell acute lymphoblastic leukemiacomplex karyotypeFUSNR3C1VPREB1

Identifiers

PMID32218851
PMCPMC7068616
OpenAlexW3006029538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.