Evidence map›Paper›PMID 32218786›Full record

ArticleFrontiers in immunology2020

Multiplex Screening Assay for Identifying Cytotoxic CD8

Chek Meng Poh, Jian Zheng, Rudragouda Channappanavar, Zi Wei Chang, Thi H O Nguyen, Laurent Rénia, Katherine Kedzierska, Stanley Perlman, Leo L M Poon

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Lipid Metabolism and Immune Function: Chemical Tools for Insights into T-Cell Biology.Chembiochem : a European journal of chemical biology · 2025
    Review
  4. Review
  5. CD8Clinical & translational immunology · 2024
    Article
  6. Time-resolved role of P2X4 and P2X7 during CD8Frontiers in immunology · 2024
    Article
  7. Review
  8. Observational
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Chek Meng PohSchool of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Jian ZhengDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.
Rudragouda ChannappanavarDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.
Zi Wei ChangSingapore Immunology Network, Agency of Science, Technology and Research, Singapore, Singapore.
Thi H O NguyenDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.
Laurent RéniaSingapore Immunology Network, Agency of Science, Technology and Research, Singapore, Singapore.
Katherine KedzierskaDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.
Stanley PerlmanDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.
Leo L M PoonSchool of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
University of Iowa · USSingapore Immunology Network · SGUniversity of Hong Kong · HKUniversity of Melbourne · AU

Funding

SARS-CoV Proteins in Heterologous Viral InfectionP01AI060699 · NIAID · UNIVERSITY OF IOWA · PI PERLMAN, STANLEY · 2004 to 2021
$21.5M
Role of eicosanoids in pathogenic human CoV infectionsR01AI129269 · NIAID · UNIVERSITY OF IOWA · PI Stanley Perlman · 2016 to 2026
$4.7M
NIAID NIH HHS HHSN272201400006CNIAID NIH HHS P01 AI060699NIAID NIH HHS R01 AI129269
6 · The paper itself

Abstract

The cytotoxicity of epitope-specific CD8

Indexed as

AnimalsEpitopes, T-LymphocyteFlow CytometryHumansMiceStaining and LabelingT-Lymphocytes, CytotoxicEpitopes, T-LymphocyteCD8 T cellcytotoxicityinfluenzaMERSmultiplex assayPlasmodium

Identifiers

PMID32218786
PMCPMC7078160
OpenAlexW3011854888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.