Evidence map›Paper›PMID 32218781›Full record

ArticleFrontiers in immunology2020

Systemic MCP-1 Levels Derive Mainly From Injured Liver and Are Associated With Complications in Cirrhosis.

Alexander Queck, Hannah Bode, Frank E Uschner, Maximilian J Brol, Christiana Graf, Martin Schulz, Christian Jansen, Michael Praktiknjo, Robert Schierwagen, Sabine Klein and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Role of cellular senescence in hepatic diseases (Review).International journal of molecular medicine · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Liver injury in cynomolgus monkeys following intravenous and intrathecal scAAV9 gene therapy delivery.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Ivermectin Attenuates CClInternational journal of molecular sciences · 2022
    Article
  20. Liver cirrhosis and immune dysfunction.International immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 3 countries.

Alexander QueckDepartment of Internal Medicine 1, University Hospital, Goethe University, Frankfurt, Germany.
Hannah BodeDepartment of Internal Medicine 1, University Hospital, University Bonn, Bonn, Germany.
Frank E UschnerDepartment of Internal Medicine 1, University Hospital, Goethe University, Frankfurt, Germany.
Maximilian J BrolDepartment of Internal Medicine 1, University Hospital, University Bonn, Bonn, Germany.
Christiana GrafDepartment of Internal Medicine 1, University Hospital, Goethe University, Frankfurt, Germany.
Martin SchulzDepartment of Internal Medicine 1, University Hospital, Goethe University, Frankfurt, Germany.
Christian JansenDepartment of Internal Medicine 1, University Hospital, University Bonn, Bonn, Germany.
Michael PraktiknjoDepartment of Internal Medicine 1, University Hospital, University Bonn, Bonn, Germany.
Robert SchierwagenDepartment of Internal Medicine 1, University Hospital, Goethe University, Frankfurt, Germany.
Sabine KleinDepartment of Internal Medicine 1, University Hospital, Goethe University, Frankfurt, Germany.
Christian TrautweinDepartment of Internal Medicine III, RTWH Aachen, Aachen, Germany.
Hermann E WasmuthDepartment of Internal Medicine III, RTWH Aachen, Aachen, Germany.
Marie-Luise BerresDepartment of Internal Medicine III, RTWH Aachen, Aachen, Germany.
Jonel TrebickaDepartment of Internal Medicine 1, University Hospital, Goethe University, Frankfurt, Germany.
Jennifer LehmannDepartment of Internal Medicine 1, University Hospital, University Bonn, Bonn, Germany.
Goethe University Frankfurt · DEUniversity Hospital Bonn · DERWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Macrophage ActivationAcute-On-Chronic Liver FailureAnimalsChemical and Drug Induced Liver InjuryChemokine CCL2Kupffer CellsLiverLiver Cirrhosis, ExperimentalMaleMiceMice, Inbred C57BLCcl2 protein, mouseChemokine CCL2acute-on-chronic liver failure (ACLF)decompensated liver cirrhosisinflammationmonocyte chemotactic protein 1 (MCP-1)transjugular intrahepatic portosystemic shunt (TIPS)

Identifiers

PMID32218781
PMCPMC7078155
OpenAlexW3011501123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.