Evidence map›Paper›PMID 32218718›Full record

ArticleFrontiers in neuroscience2020

Rethinking Schizophrenia and Depression Comorbidity as One Psychiatric Disorder Entity: Evidence From Mouse Model.

Chunhua Zhou, Dezhi Kong, Xiaodong Zhu, Wei Wu, Rong Xue, Gongying Li, Yong Xu, Sha Liu, Hongjun Tian, Chuanjun Zhuo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Chunhua ZhouDepartment of Pharmacology, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Dezhi KongTwo-Photon In Vivo Imaging Centre, Institute of Chinese Integrative Medicine, Hebei Medical University, Shijiazhuang, China.
Xiaodong ZhuTianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.
Wei WuTianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.
Rong XueTianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.
Gongying LiInstitute of Brain Micro Scale Imaging Centre, School of Mental Health, Jining Medical University, Jining, China.
Yong XuMDT Center for Cognitive Impairment and Sleep Disorders, First Hospital/First Clinical Medical College of Shanxi Medical University, Taiyuan, China.
Sha LiuMDT Center for Cognitive Impairment and Sleep Disorders, First Hospital/First Clinical Medical College of Shanxi Medical University, Taiyuan, China.
Hongjun TianPsychiatric-Neuroimaging-Genetics-Comorbidity Laboratory (PNGC_Lab), Tianjin Mental Health Centre, Mental Health Teaching Hospital of Tianjin Medical University, Tianjin Anding Hospital, Tianjin, China.
Chuanjun ZhuoInstitute of Brain Micro Scale Imaging Centre, School of Mental Health, Jining Medical University, Jining, China.
Shanxi Medical University · CNTianjin Medical University General Hospital · CNHebei Medical University · CNJining Medical University · CNTianjin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizophrenia is frequently accompanied by depressive symptoms, but the pathological mechanisms remain to be elucidated. In this study, we used chronic unpredicted mild stress plus MK801 injection to generate a mouse model of schizophrenia with depression, in which

Indexed as

antipsychotic treatmentbehavioral phenotypesdepressionmouse modelprefrontal cortex neuronal activityschizophrenia

Identifiers

PMID32218718
PMCPMC7078335
OpenAlexW3011426866

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.