Evidence map›Paper›PMID 32218705›Full record

ArticleInternational journal of medical sciences2020

Action of low doses of Aspirin in Inflammation and Oxidative Stress induced by aβ

Adrian Jorda, Martin Aldasoro, Constanza Aldasoro, Sol Guerra-Ojeda, Antonio Iradi, Jose Mª Vila, Juan Campos-Campos, Soraya L Valles

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 35 citations in OpenAlex.

  1. Platelet count polygenic scores may modify the effect of aspirin in primary prevention of dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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  14. Exploring the role of COX-2 in Alzheimer's disease: Potential therapeutic implications of COX-2 inhibitors.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Adrian JordaDepartment of Physiology, School of Medicine, University of Valencia, Spain.
Martin AldasoroDepartment of Physiology, School of Medicine, University of Valencia, Spain.
Constanza AldasoroDepartment of Physiology, School of Medicine, University of Valencia, Spain.
Sol Guerra-OjedaDepartment of Physiology, School of Medicine, University of Valencia, Spain.
Antonio IradiDepartment of Physiology, School of Medicine, University of Valencia, Spain.
Jose Mª VilaDepartment of Physiology, School of Medicine, University of Valencia, Spain.
Juan Campos-CamposDepartment of Physiology, School of Medicine, University of Valencia, Spain.
Soraya L VallesDepartment of Physiology, School of Medicine, University of Valencia, Spain.
Universitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspirin has been used as anti-inflammatory and anti-aggregate for decades but the precise mechanism(s) of action after the presence of the toxic peptide Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsAspirinAstrocytesCell ProliferationCell SurvivalDose-Response Relationship, DrugGene Expression RegulationHumansInflammationInterleukin-1betaNF-kappa BOxidative StressPeptide FragmentsPrimary Cell CultureAmyloid beta-Peptidesamyloid beta-protein (1-42)AspirinInterleukin-1betaNF-kappa BPeptide FragmentsTumor Necrosis Factor-alphaAlzheimer's diseaseAmyloid-βaspirininflammationoxidative stress

Identifiers

PMID32218705
PMCPMC7085272
OpenAlexW3012568259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.