ArticleMolecular and cellular biology1988
Differential expression of a tropomyosin isoform in low- and high-metastatic Lewis lung carcinoma cells.
Article in Molecular and cellular biology, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 37 citations in OpenAlex.
- Downregulated Expression of Tropomyosin 1 in Intrahepatic Cholangiocarcinoma: A Predictor of Recurrence and Prognosis.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- KSHV MicroRNAs Repress Tropomyosin 1 and Increase Anchorage-Independent Growth and Endothelial Tube Formation.PloS one · 2015Article
- Human diploid fibroblasts are resistant to MEK/ERK-mediated disruption of the actin cytoskeleton and invasiveness stimulated by Ras.Oncogene · 2005Article
- Application of proteomics in the study of tumor metastasis.Genomics, proteomics & bioinformatics · 2004Review
- The antiangiogenic activity of cleaved high molecular weight kininogen is mediated through binding to endothelial cell tropomyosin.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Opposing roles of the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in Ras-mediated downregulation of tropomyosin.Molecular and cellular biology · 2002Article
- Transduction of HOXD3-antisense into human melanoma cells results in decreased invasive and motile activities.Clinical & experimental metastasis · 2002Article
- Involvement of S100-related calcium-binding protein pEL98 (or mts1) in cell motility and tumor cell invasion.Japanese journal of cancer research : Gann · 1994Article
- Binding of pEL98 protein, an S100-related calcium-binding protein, to nonmuscle tropomyosin.The Journal of cell biology · 1994Article
- Repression of stromelysin metalloprotease expression in rat fibrosarcoma cells by dimethylsulfoxide.Clinical & experimental metastasis · 1993Article
- Morphological characteristics of tumours formed by Lewis lung carcinoma-derived cloned cell lines with different metastatic potentials: structural differences in their basement membranes formed in vivo.Virchows Archiv. A, Pathological anatomy and histopathology · 1992Article
- Isolation and characterization of a cDNA that encodes mouse fibroblast tropomyosin isoform 2.Molecular and cellular biology · 1988Article
- Expression of a specific protein in spontaneously metastatic fibrosarcoma cell lines and its enhanced synthesis by growth on laminin or fibronectin.Clinical & experimental metastasisArticle
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3 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Two-dimensional electrophoretograms of newly synthesized polypeptides from low-metastatic (P29) and high-metastatic (D6) Lewis lung carcinoma cells were compared. The results showed that the synthesis of tropomyosin 2 (TM2) was significantly less in D6 cells than in P29 cells. Furthermore, suppression of TM2 synthesis was induced in P29 cells during incubation in medium containing dimethyl sulfoxide or butyric acid, which induced the metastatic phenotype of P29 cells. These results suggest that the suppression of TM2 synthesis is linked to the metastatic potential of Lewis lung carcinoma cells.
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