Evidence map›Paper›PMID 3221869›Full record

ArticleMolecular and cellular biology1988

Isolation of cDNA clones for mouse cytoskeletal gamma-actin and differential expression of cytoskeletal actin mRNAs in mouse cells.

K Tokunaga, K Takeda, K Kamiyama, H Kageyama, K Takenaga, S Sakiyama

Open access · greenAbstract readComparative Study
In one paragraph

Article in Molecular and cellular biology, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 30 citations in OpenAlex.

  1. Cytoplasmic gamma-actin contributes to a compensatory remodeling response in dystrophin-deficient muscle.Proceedings of the National Academy of Sciences of the United States of America · 2006
    Article
  2. Article
  3. Article
  4. Mouse map of paralogous genes.Mammalian genome : official journal of the International Mammalian Genome Society · 1991
    Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

K TokunagaDivision of Biochemistry, Chiba Cancer Center Research Institute, Japan.
K Takeda
K Kamiyama
H Kageyama
K Takenaga
S Sakiyama
Chiba Cancer Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We described the structures of mouse cytoskeletal gamma-actin cDNA clones and showed that there is strong conservation of the untranslated regions with human gamma-actin cDNA. In addition, we found that the expression levels of beta- and gamma-actin mRNAs are differentially controlled in various mouse tissues and cell types but are coordinately increased in the cellular growing state. These results suggest that there are multiple regulatory mechanisms of cytoskeletal actin genes and are consistent with the argument that beta- and gamma-actins might have functional diversity in mammalian cells.

Indexed as

Cloning, MolecularGenesTranscription, GeneticActinsAmino Acid SequenceAnimalsBase SequenceCells, CulturedCytoskeletonDNAHumansMiceMolecular Sequence DataRNA, MessengerSequence Homology, Nucleic AcidSpecies SpecificityActinsDNARNA, Messenger

Identifiers

PMID3221869
PMCPMC365452
OpenAlexW1848341504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.