Evidence map›Paper›PMID 32218534›Full record

ReviewPediatric research2020

Preterm white matter injury: ultrasound diagnosis and classification.

Thais Agut, Ana Alarcon, Fernando Cabañas, Marco Bartocci, Miriam Martinez-Biarge, Sandra Horsch, eurUS.brain group

Open access · hybridAbstract readReview
In one paragraph

Review in Pediatric research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 125 citations in OpenAlex.

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  18. A Specific Haplotype of theDiagnostics (Basel, Switzerland) · 2025
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  19. A head start: The relationship of placental factors to craniofacial and brain development.Developmental dynamics : an official publication of the American Association of Anatomists · 2025
    Review
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Thais AgutDepartment of Neonatology, Hospital Sant Joan de Déu, Institut de Recerca Sant Joan de Déu, Barcelona, Spain. tagut@sjdhospitalbarcelona.org.
Ana AlarconDepartment of Neonatology, Hospital Sant Joan de Déu, Institut de Recerca Sant Joan de Déu, Barcelona, Spain.
Fernando CabañasDepartment of Neonatology, Quironsalud Madrid University Hospital and Biomedical Research Foundation, La Paz University Hospital Madrid, Madrid, Spain.
Marco BartocciDepartment of Women's and Children's Health, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden.
Miriam Martinez-BiargeDepartment of Paediatrics, Imperial College London, London, UK.
Sandra HorschDepartment of Neonatology, Helios Klinikum Berlin Buch, Berlin, Germany.
eurUS.brain group
Hospital Sant Joan de Déu Barcelona · ESKarolinska University Hospital · SEHelios Hospital Berlin-Buch · DEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

White matter injury (WMI) is the most frequent form of preterm brain injury. Cranial ultrasound (CUS) remains the preferred modality for initial and sequential neuroimaging in preterm infants, and is reliable for the diagnosis of cystic periventricular leukomalacia. Although magnetic resonance imaging is superior to CUS in detecting the diffuse and more subtle forms of WMI that prevail in very premature infants surviving nowadays, recent improvement in the quality of neonatal CUS imaging has broadened the spectrum of preterm white matter abnormalities that can be detected with this technique. We propose a structured CUS assessment of WMI of prematurity that seeks to account for both cystic and non-cystic changes, as well as signs of white matter loss and impaired brain growth and maturation, at or near term equivalent age. This novel assessment system aims to improve disease description in both routine clinical practice and clinical research. Whether this systematic assessment will improve prediction of outcome in preterm infants with WMI still needs to be evaluated in prospective studies.

Indexed as

BrainBrain InjuriesEchoencephalographyHumansInfantInfant, NewbornInfant, PrematureInfant, Premature, DiseasesLeukomalacia, PeriventricularMagnetic Resonance ImagingNeonatologyPredictive Value of TestsWhite Matter

Identifiers

PMID32218534
PMCPMC7098888
OpenAlexW3013245817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.