Evidence map›Paper›PMID 32218519›Full record

ArticleScientific reports2020

In vitro modelling of alveolar repair at the air-liquid interface using alveolar epithelial cells derived from human induced pluripotent stem cells.

Sander van Riet, Dennis K Ninaber, Harald M M Mikkers, Teresa D Tetley, Carolina R Jost, Aat A Mulder, Thijs Pasman, Danielle Baptista, André A Poot, Roman Truckenmüller and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Review
  10. Article
  11. HumanTissue barriers · 2024
    Review
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  17. Review
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  19. Article
  20. Lung-on-a-Chip Models of the Lung Parenchyma.Advances in experimental medicine and biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sander van RietDepartment of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands. s.van_riet@lumc.nl.
Dennis K NinaberDepartment of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands.
Harald M M MikkersDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
Teresa D TetleyNational Heart & Lung Institute, Imperial College London, London, United Kingdom.
Carolina R JostDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0001-8342-1094
Aat A MulderDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
Thijs PasmanDepartment of Biomaterials Science and Technology, Technical Medical (TechMed) Centre, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands.
Danielle BaptistaDepartment of Instructive Biomaterials Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands.
André A PootDepartment of Biomaterials Science and Technology, Technical Medical (TechMed) Centre, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands.
Roman TruckenmüllerDepartment of Instructive Biomaterials Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands.
Christine L MummeryDepartment of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.
Christian FreundLUMC hiPSC core facility, Leiden University Medical Center, Leiden, The Netherlands.
Robbert J RottierDepartment of Pediatric Surgery, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.
Pieter S HiemstraDepartment of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands. p.s.hiemstra@lumc.nl.ORCID http://orcid.org/0000-0002-0238-5982

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research on acute and chronic lung diseases would greatly benefit from reproducible availability of alveolar epithelial cells (AEC). Primary alveolar epithelial cells can be derived from human lung tissue but the quality of these cells is highly donor dependent. Here, we demonstrated that culture of EpCAM

Indexed as

Models, BiologicalAlveolar Epithelial CellsCell DifferentiationCell LineCells, CulturedHumansInduced Pluripotent Stem CellsIn Vitro TechniquesPulmonary AlveoliRegenerationWound Healing

Identifiers

PMID32218519
PMCPMC7099095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.