Evidence map›Paper›PMID 32218486›Full record

ArticleScientific reports2020

Patterns of Rift Valley fever virus seropositivity in domestic ruminants in central South Africa four years after a large outbreak.

Yusuf B Ngoshe, Alida Avenant, Melinda K Rostal, William B Karesh, Janusz T Paweska, Whitney Bagge, Petrus Jansen van Vuren, Alan Kemp, Claudia Cordel, Veerle Msimang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  10. Seroprevalence ofFrontiers in veterinary science · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Yusuf B NgosheEpidemiology Section, Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110, South Africa.
Alida AvenantEpidemiology Section, Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110, South Africa.
Melinda K RostalEcoHealth Alliance, 460 West 34th Street - 17th Floor, New York, NY, 10001, USA.
William B KareshEcoHealth Alliance, 460 West 34th Street - 17th Floor, New York, NY, 10001, USA.
Janusz T PaweskaCentre for Emerging Zoonotic & Parasitic Diseases, National Institute for Communicable Diseases, National Health Laboratory Service, Sandringham, Johannesburg, South Africa.ORCID http://orcid.org/0000-0001-8776-7519
Whitney BaggeEcoHealth Alliance, 460 West 34th Street - 17th Floor, New York, NY, 10001, USA.
Petrus Jansen van VurenCentre for Emerging Zoonotic & Parasitic Diseases, National Institute for Communicable Diseases, National Health Laboratory Service, Sandringham, Johannesburg, South Africa.
Alan KempCentre for Emerging Zoonotic & Parasitic Diseases, National Institute for Communicable Diseases, National Health Laboratory Service, Sandringham, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-2051-467X
Claudia CordelExecuVet, Kenilworth Road, Bloemfontein, South Africa.
Veerle MsimangEpidemiology Section, Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110, South Africa.
Peter N ThompsonEpidemiology Section, Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110, South Africa. peter.thompson@up.ac.za.ORCID http://orcid.org/0000-0002-2268-9748
National Health Laboratory Service · ZAEcoHealth Alliance · USOnderstepoort Veterinary Academic Hospital · ZAClinvet · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rift Valley fever (RVF) is a mosquito-borne viral zoonosis showing complex epidemiological patterns that are poorly understood in South Africa. Large outbreaks occur in the central interior at long, irregular intervals, most recently in 2010-2011; however, the level of herd immunity of ruminant livestock, a key determinant of outbreaks, is unknown. During 2015-2016 a cross-sectional study on 234 randomly-selected farms investigated the prevalence, patterns of, and factors associated with, antibodies to RVF virus (RVFV) in livestock in an area heavily affected by that outbreak. A RVFV inhibition ELISA was used to screen 977 cattle, 1,549 sheep and 523 goats and information on potential risk factors was collected using a comprehensive questionnaire. The estimated RVFV seroprevalence, adjusted for survey design, was 42.9% in cattle, 28.0% in sheep and 9.3% in goats, showing a high degree of farm-level clustering. Seroprevalence increased with age and was higher on private vs. communal land, on farms with seasonal pans (temporary, shallow wetlands) and perennial rivers and in recently vaccinated animals. Seropositivity amongst unvaccinated animals born after the last outbreak indicates likely viral circulation during the post-epidemic period. The current level of herd immunity in livestock may be insufficient to prevent another large outbreak, should suitable conditions recur.

Indexed as

AnimalsAntibodies, ViralCattleCattle DiseasesCross-Sectional StudiesDisease OutbreaksFemaleGoat DiseasesGoatsImmunity, HerdMaleRift Valley FeverRift Valley fever virusRisk FactorsSeroepidemiologic StudiesSheepAntibodies, Viral

Identifiers

PMID32218486
PMCPMC7099094
OpenAlexW3014070930

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.