Evidence map›Paper›PMID 32218474›Full record

ArticleScientific reports2020

Evaluating the potential of hyperpolarised [1-

Jean-Noël Hyacinthe, Lara Buscemi, Thanh Phong Lê, Mario Lepore, Lorenz Hirt, Mor Mishkovsky

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Review
  3. Tracking Hyperpolarized [1-NMR in biomedicine · 2025
    Article
  4. Article
  5. Isoflurane titration improves detection of hippocampal lactate byImaging neuroscience (Cambridge, Mass.) · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Epigenetic MRI: Noninvasive imaging of DNA methylation in the brain.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  12. Review
  13. Review
  14. Metabolic MRI with hyperpolarized [1-Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  15. Article
  16. HyperpolarizedScientific reports · 2021
    Article
  17. HyperpolarizedBiomedicines · 2021
    Article
  18. A Splice Variant inCells · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Jean-Noël Hyacinthe *Geneva School of Health Sciences, HES-SO University of Applied Sciences and Arts Western Switzerland, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-6983-0956
Lara Buscemi *Department of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.ORCID http://orcid.org/0000-0001-8564-649X
Thanh Phong LêGeneva School of Health Sciences, HES-SO University of Applied Sciences and Arts Western Switzerland, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-9615-5642
Mario LeporeCentre d'Imagerie Biomédicale (CIBM), École polytechnique fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Lorenz HirtDepartment of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-2921-5000
Mor MishkovskyLaboratory of Functional and Metabolic Imaging, École polytechnique fédérale de Lausanne (EPFL), Lausanne, Switzerland. mor.mishkovsky@epfl.ch.ORCID http://orcid.org/0000-0001-6816-7462
University Hospital of Lausanne · CHCentre d'Imagerie BioMedicale · CHÉcole Polytechnique Fédérale de Lausanne · CHHES-SO University of Applied Sciences and Arts Western Switzerland · CHUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral metabolism, which can be monitored by magnetic resonance spectroscopy (MRS), changes rapidly after brain ischaemic injury. Hyperpolarisation techniques boost

Indexed as

AnimalsBicarbonatesBiosensing TechniquesBrain IschemiaCarbon IsotopesComputer SystemsDisease Models, AnimalFeasibility StudiesHumansImmunohistochemistryInfarction, Middle Cerebral ArteryLactic AcidMagnetic Resonance SpectroscopyMaleMiceMice, Inbred C57BLBicarbonatesCarbon-13Carbon IsotopesLactic AcidMonocarboxylic Acid TransportersNeuroprotective AgentsPyruvic Acid

Identifiers

PMID32218474
PMCPMC7099080
OpenAlexW3014061784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.