ArticleScientific data2020
Generation of a murine SWATH-MS spectral library to quantify more than 11,000 proteins.
Article in Scientific data, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- A Labrador PeptideAtlas and DIA spectral assay library - resources for proteomics research in dogs.Scientific data · 2026Article
- A reference database enabling in-depth proteome and PTM analysis of mouse immune cells.Scientific data · 2025Article
- Optimal Sample Preparation Workflow for Quantitative Mass Spectrometry-Based Studies in the Low Range.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Grape-Pi: graph-based neural networks for enhanced protein identification in proteomics pipelines.Bioinformatics advances · 2025Article
- Proteome-wide copy-number estimation from transcriptomics.Molecular systems biology · 2024Article
- Deep Spectral Library of Mice Retina for Myopia Research: Proteomics Dataset generated by SWATH and DIA-NN.Scientific data · 2024Article
- Vascular Proteome Responses Precede Organ Dysfunction in a Murine Model of Staphylococcus aureus Bacteremia.mSystems · 2022Article
- Baseline proteomics characterisation of the emerging host biomanufacturing organism Halomonas bluephagenesis.Scientific data · 2022Article
- Article
- Generation of a mouse SWATH-MS spectral library to quantify 10148 proteins involved in cell reprogramming.Scientific data · 2021Article
- High-pH reversed-phase fractionated neural retina proteome of normal growing C57BL/6 mouse.Scientific data · 2021Article
- A comprehensive spectral assay library to quantify the Escherichia coli proteome by DIA/SWATH-MS.Scientific data · 2020Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Targeted SWATH-MS data analysis is critically dependent on the spectral library. Comprehensive spectral libraries of human or several other organisms have been published, but the extensive spectral library for mouse, a widely used model organism is not available. Here, we present a large murine spectral library covering more than 11,000 proteins and 240,000 proteotypic peptides, which included proteins derived from 9 murine tissue samples and one murine L929 cell line. This resource supports the quantification of 67% of all murine proteins annotated by UniProtKB/Swiss-Prot. Furthermore, we applied the spectral library to SWATH-MS data from murine tissue samples. Data are available via SWATHAtlas (PASS01441).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.