ArticleNature communications2020
Ionic amplifying circuits inspired by electronics and biology.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- The Power of Tiny Spaces.JACS Au · 2026Review
- Bioinspired Nanofluidic Memristors Based on Polyelectrolyte Conformation for Synaptic Learning and in-Memory Logic Computing.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Electrostatic Gating of Ionic Conductance through Heterogeneous van der Waals Nanopores.ACS nano · 2026Article
- A nanofluidic oscillating neuron.Nature communications · 2025Article
- Anodized Aluminum Oxide Membrane Ionic Memristors.Journal of the American Chemical Society · 2025Article
- Geometrically Scalable Iontronic Memristors: Employing Bipolar Polyelectrolyte Gels for Neuromorphic Systems.ACS nano · 2024Article
- Bioinspired carbon nanotube-based nanofluidic ionic transistor with ultrahigh switching capabilities for logic circuits.Science advances · 2024Article
- Low-cost and convenient fabrication of polymer micro/nanopores with the needle punching process and their applications in nanofluidic sensing.Biomicrofluidics · 2024Article
- Designing with Iontronic Logic Gates─From a Single Polyelectrolyte Diode to an Integrated Ionic Circuit.ACS applied materials & interfaces · 2023Article
- Fluids and Electrolytes under Confinement in Single-Digit Nanopores.Chemical reviews · 2023Review
- Multifunctional graphene heterogeneous nanochannel with voltage-tunable ion selectivity.Nature communications · 2022Article
- Rectified and Salt Concentration Dependent Wetting of Hydrophobic Nanopores.Journal of the American Chemical Society · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Integrated circuits are present in all electronic devices, and enable signal amplification, modulation, and relay. Nature uses another type of circuits composed of channels in a cell membrane, which regulate and amplify transport of ions, not electrons and holes as is done in electronic systems. Here we show an abiotic ionic circuit that is inspired by concepts from electronics and biology. The circuit amplifies small ionic signals into ionic outputs, and its operation mimics the electronic Darlington amplifier composed of transistors. The individual transistors are pores equipped with three terminals including a gate that is able to enrich or deplete ions in the pore. The circuits we report function at gate voltages < 1 V, respond to sub-nA gate currents, and offer ion current amplification with a gain up to ~300. Ionic amplifiers are a logical step toward improving chemical and biochemical sensing, separations and amplification, among others.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.