ArticleMicromachines2020
AC Electroosmosis Effect on Microfluidic Heterogeneous Immunoassay Efficiency.
Article in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Numerical optimization of microfluidic biosensor detection time for the SARS-CoV-2 using the Taguchi method.Indian journal of physics and proceedings of the Indian Association for the Cultivation of Science (2004) · 2023Article
- AC-Electroosmosis-Assisted Surface Plasmon Resonance Sensing for Enhancing Protein Signals with a Simple Kretschmann Configuration.Sensors (Basel, Switzerland) · 2022Article
- 3D simulation of microfluidic biosensor for SARS-CoV-2 S protein binding kinetics using new reaction surface design.European physical journal plus · 2022Article
- Analysis of Temperature-Jump Boundary Conditions on Heat Transfer for Heterogeneous Microfluidic Immunosensors.Sensors (Basel, Switzerland) · 2021Article
- Enhancement of COVID-19 detection time by means of electrothermal force.Microfluidics and nanofluidics · 2021Article
- Application of Microfluidics in Immunoassay: Recent Advancements.Journal of healthcare engineering · 2021Review
- Simulation of the Slip Velocity Effect in an AC Electrothermal Micropump.Micromachines · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A heterogeneous immunoassay is an efficient biomedical test. It aims to detect the presence of an analyte or to measure its concentration. It has many applications, such as manipulating particles and separating cancer cells from blood. The enhanced performance of immunosensors comes down to capturing more antigens with greater efficiency by antibodies in a short time. In this work, we report an efficient investigation of the effects of alternating current (AC) electrokinetic forces such as AC electroosmosis (ACEO), which arise when the fluid absorbs energy from an applied electric field, on the kinetics of the antigen-antibody binding in a flow system. The force can produce swirling structures in the fluid and, thus, improve the transport of the analyte toward the reaction surface of the immunosensor device. A numerical simulation is adequate for this purpose and may provide valuable information. The convection-diffusion phenomenon is coupled with the first-order Langmuir model. The governing equations are solved using the finite element method (FEM). The impact of AC electroosmosis on the binding reaction kinetics, the fluid flow stream modification, the analyte concentration diffusion, and the detection time of the biosensor under AC electroosmosis are analyzed.
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Registered trials
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