Evidence map›Paper›PMID 32218209›Full record

ArticleMolecules (Basel, Switzerland)2020

New Substituted Benzoylthiourea Derivatives: From Design to Antimicrobial Applications.

Carmen Limban, Mariana Carmen Chifiriuc, Miron Teodor Caproiu, Florea Dumitrascu, Marilena Ferbinteanu, Lucia Pintilie, Amalia Stefaniu, Ilinca Margareta Vlad, Coralia Bleotu, Luminita Gabriela Marutescu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. ACS omega · 2022
    Article
  10. Article
  11. Diaryl Urea Derivative Molecule Inhibits CariogenicFrontiers in cellular and infection microbiology · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Carmen LimbanDepartment of Pharmaceutical Chemistry, "Carol Davila" University of Medicine and Pharmacy, 020956 Bucharest, Romania.
Mariana Carmen ChifiriucDepartment of Microbiology, Faculty of Biology & Research Institute of the University of Bucharest (ICUB), University of Bucharest, 060101 Bucharest, Romania.
Miron Teodor CaproiuThe Organic Chemistry Center of Romanian Academy "C. D. Neniţescu", 060023 Bucharest, Romania.
Florea DumitrascuThe Organic Chemistry Center of Romanian Academy "C. D. Neniţescu", 060023 Bucharest, Romania.
Marilena FerbinteanuInorganic Chemistry Department, Faculty of Chemistry, University of Bucharest, 020462 Bucharest, Romania.
Lucia PintilieNational Institute of Chemical-Pharmaceutical Research & Development, 031299 Bucharest, Romania.ORCID 0000-0002-1036-7653
Amalia StefaniuNational Institute of Chemical-Pharmaceutical Research & Development, 031299 Bucharest, Romania.
Ilinca Margareta VladDepartment of Pharmaceutical Chemistry, "Carol Davila" University of Medicine and Pharmacy, 020956 Bucharest, Romania.
Coralia BleotuStefan S. Nicolau Institute of Virology, Mihai Bravu 285, Bucharest, 030304, Romania.ORCID 0000-0002-9031-338X
Luminita Gabriela MarutescuDepartment of Microbiology, Faculty of Biology & Research Institute of the University of Bucharest (ICUB), University of Bucharest, 060101 Bucharest, Romania.
Diana Camelia NutaDepartment of Pharmaceutical Chemistry, "Carol Davila" University of Medicine and Pharmacy, 020956 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROUniversity of Bucharest · RONational Institute For Chemical Pharmaceutical Research and Development · RORomanian Academy · RO

Funding

UEFISCDI PN-III-P4-ID-PCCF-2016-0114 (RADAR)
6 · The paper itself

Abstract

The increasing threat of antimicrobial resistance to all currently available therapeutic agents has urged the development of novel antimicrobials. In this context, a series of new benzoylthiourea derivatives substituted with one or more fluorine atoms and with the trifluoromethyl group have been tested, synthesized, and characterized by IR, NMR, CHNS and crystal X-ray diffraction. The molecular docking has provided information regarding the binding affinity and the orientation of the new compounds to

Indexed as

Drug DesignAnti-Bacterial AgentsBacteriaBinding SitesBiofilmsFungiLigandsMicrobial Sensitivity TestsMolecular ConformationMolecular Docking SimulationStatic ElectricityThioureaAnti-Bacterial AgentsLigandsN-benzoylthioureaThioureaantibiofilmantimicrobialbenzoylthiourea derivativesin silicoX-ray

Identifiers

PMID32218209
PMCPMC7180980
OpenAlexW3014009822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.