Evidence map›Paper›PMID 32217665›Full record

ArticleGenes & development2020

The rRNA m

Valentina V Ignatova, Paul Stolz, Steffen Kaiser, Tobias H Gustafsson, Palma Rico Lastres, Adrián Sanz-Moreno, Yi-Li Cho, Oana V Amarie, Antonio Aguilar-Pimentel, Tanja Klein-Rodewald and 21 more

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 142 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Methylation marks breast cancer metastasis: The roles of mThe Journal of biological chemistry · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Inhibition ofACS omega · 2025
    Article
  10. Article
  11. Inhibition ofbioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. VIRMA-mediated mScience advances · 2025
    Article
  14. Review
  15. Review
  16. Review
  17. Regulation and application of mScience China. Life sciences · 2025
    Review
  18. Exploring the methyl-verse: Dynamic interplay of epigenome and m6A epitranscriptome.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  19. Review
  20. Review

37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 7 institutions in 3 countries.

Valentina V IgnatovaInstitute of Functional Epigenetics, Helmholtz Zentrum München (HMGU), Neuherberg 85764, Germany.
Paul StolzDepartment of Biology II, Human Biology, and BioImaging, Ludwig-Maximilians Universität München, Munich 81377, Germany.
Steffen KaiserChemical Faculty, Ludwig-Maximilians Universität München, Munich 81377, Germany.
Tobias H GustafssonUniversity of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
Palma Rico LastresInstitute of Functional Epigenetics, Helmholtz Zentrum München (HMGU), Neuherberg 85764, Germany.
Adrián Sanz-MorenoGerman Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.
Yi-Li ChoGerman Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.
Oana V AmarieGerman Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.
Antonio Aguilar-PimentelGerman Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.
Tanja Klein-RodewaldGerman Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.
Julia Calzada-WackGerman Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.
Lore BeckerGerman Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.
Susan MarschallGerman Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.
Markus KraigerGerman Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.
Lillian GarrettGerman Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.
Claudia SeisenbergerInstitute of Developmental Genetics, HMGU, Neuherberg 85764, Germany.
Sabine M HölterGerman Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.
Kayla BorlandChemical Faculty, Ludwig-Maximilians Universität München, Munich 81377, Germany.
Erik Van De LogtChemical Faculty, Ludwig-Maximilians Universität München, Munich 81377, Germany.
Pascal W T C JansenDepartment of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, GA Nijmegen 6525, the Netherlands.
Marijke P BaltissenDepartment of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, GA Nijmegen 6525, the Netherlands.
Magdalena ValentaInstitute of Functional Epigenetics, Helmholtz Zentrum München (HMGU), Neuherberg 85764, Germany.
Michiel VermeulenDepartment of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, GA Nijmegen 6525, the Netherlands.
Wolfgang WurstInstitute of Developmental Genetics, HMGU, Neuherberg 85764, Germany.
Valerie Gailus-DurnerGerman Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.
Helmut FuchsGerman Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.
Martin Hrabe de AngelisGerman Mouse Clinic, Institute of Experimental Genetics, HMGU, Neuherberg 85764, Germany.
Oliver J RandoUniversity of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
Stefanie M KellnerChemical Faculty, Ludwig-Maximilians Universität München, Munich 81377, Germany.
Sebastian BultmannDepartment of Biology II, Human Biology, and BioImaging, Ludwig-Maximilians Universität München, Munich 81377, Germany.
Robert SchneiderInstitute of Functional Epigenetics, Helmholtz Zentrum München (HMGU), Neuherberg 85764, Germany.
Ludwig-Maximilians-Universität München · DEHelmholtz Zentrum München · DEOncode Institute · NLUniversity of Massachusetts Chan Medical School · USGerman Center for Neurodegenerative Diseases · DEHeinrich Heine University Düsseldorf · DERadboud University Medical Center · NL

Funding

Dietary effects on the sperm epigenomeR01HD080224 · NICHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI RANDO, OLIVER J · 2014 to 2022
$5.9M
NICHD NIH HHS R01 HD080224
6 · The paper itself

Abstract

Covalent chemical modifications of cellular RNAs directly impact all biological processes. However, our mechanistic understanding of the enzymes catalyzing these modifications, their substrates and biological functions, remains vague. Amongst RNA modifications N

Indexed as

AdenosineAnimalsCell DifferentiationGene Expression Regulation, DevelopmentalMiceMouse Embryonic Stem CellsMutationPluripotent Stem CellsProtein BiosynthesisRNA, Ribosomal, 18SAdenosineN-methyladenosineRNA, Ribosomal, 18Sm6Amethyltransferasepluripotency

Identifiers

PMID32217665
PMCPMC7197354
OpenAlexW3012987339

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.