Evidence map›Paper›PMID 32217654›Full record

ArticleThe European respiratory journal2020

The natural history of progressive fibrosing interstitial lung diseases.

Kevin K Brown, Fernando J Martinez, Simon L F Walsh, Victor J Thannickal, Antje Prasse, Rozsa Schlenker-Herceg, Rainer-Georg Goeldner, Emmanuelle Clerisme-Beaty, Kay Tetzlaff, Vincent Cottin and 1 more

Abstract read
In one paragraph

Article in The European respiratory journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 148 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
148citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

148 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  19. Prevalence and Prognostic Impact of Progressive Pulmonary Fibrosis.Tuberculosis and respiratory diseases · 2026
    Review
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88 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Kevin K BrownDept of Medicine, National Jewish Health, Denver, CO, USA brownk@njhealth.org.
Fernando J MartinezDept of Medicine, Weill Cornell Medicine, New York, NY, USA.
Simon L F WalshNational Heart and Lung Institute, Imperial College, London, UK.
Victor J ThannickalDivision of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Antje PrasseDept of Respiratory Medicine, MHH Hannover Medical School and Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Deutsches Zentrum für Lungenforschung (DZL), Hannover, Germany.ORCID 0000-0002-7336-7458
Rozsa Schlenker-HercegBoehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA.
Rainer-Georg GoeldnerBoehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
Emmanuelle Clerisme-BeatyBoehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany.
Kay TetzlaffBoehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany.
Vincent CottinNational Reference Centre for Rare Pulmonary Diseases, Louis Pradel Hospital, Hospices Civils de Lyon, UMR 754, Claude Bernard University Lyon 1, Lyon, France.ORCID 0000-0002-5591-0955
Athol U WellsNational Heart and Lung Institute, Imperial College, London, UK.

Funding

Therapeutic Targeting of the Myofibroblast in Fibrotic Lung DiseaseP01HL114470 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI THANNICKAL, VICTOR J. · 2013 to 2022
$17.8M
Department of Health CS-2018-18-ST2-004NHLBI NIH HHS P01 HL114470
6 · The paper itself

Abstract

We used data from the INBUILD and INPULSIS trials to investigate the natural history of progressive fibrosing interstitial lung diseases (ILDs).Subjects in the two INPULSIS trials had a clinical diagnosis of idiopathic pulmonary fibrosis (IPF) while subjects in the INBUILD trial had a progressive fibrosing ILD other than IPF and met protocol-defined criteria for ILD progression despite management. Using data from the placebo groups, we compared the rate of decline in forced vital capacity (FVC) (mL·year

Indexed as

Idiopathic Pulmonary FibrosisLung Diseases, InterstitialAgedDisease ProgressionFemaleHumansIndolesMaleMiddle AgedVital CapacityIndoles

Identifiers

PMID32217654
PMCPMC7315005

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.