Evidence map›Paper›PMID 32217055›Full record

ArticleAcademic radiology2021

Paired CT Measures of Emphysema and Small Airways Disease and Lung Function and Exercise Capacity in Smokers with Radiographic Bronchiectasis.

Carlos H Martinez, Yuka Okajima, Andrew Yen, Diego J Maselli, Pietro Nardelli, Farbord Rahaghi, Kendra Young, Gregory Kinney, Charles Hatt, Craig Galban and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Academic radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. CT-Based Commercial Software Applications: Improving Patient Care Through Accurate COPD Subtyping.International journal of chronic obstructive pulmonary disease · 2022
    Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Carlos H MartinezOaklawn Medical Group, Marshall, Michigan.
Yuka OkajimaDepartment of Radiology, St. Luke's International Hospital, Chuo-ku, Tokyo.
Andrew YenDepartment of Radiology, University of California San Diego, San Diego, California.
Diego J MaselliDivision of Pulmonary Diseases & Critical Care, University of Texas Health Science Center, San Antonio, Texas.
Pietro NardelliDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Farbord RahaghiDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, Massachusetts.
Kendra YoungColorado School of Public Health, University of Colorado Denver, Aurora, Colorado.
Gregory KinneyColorado School of Public Health, University of Colorado Denver, Aurora, Colorado.
Charles HattImbio LCC, Minneapolis, Minnesota.
Craig GalbanDepartment of Radiology, University of Michigan, Ann Arbor, Michigan.
George R WashkoDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, Massachusetts.
MeiLan HanDivision of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, Michigan.
Raúl San José EstéparDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Alejandro A DiazDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, Massachusetts. Electronic address: ADiaz6@bwh.harvard.edu.
Brigham and Women's Hospital · USColorado School of Public Health · USUniversity of Michigan · USImbio (United States) · USSt. Luke's International Hospital · JPThe University of Texas Health Science Center at San Antonio · USUniversity of California San Diego · US

Funding

Metabolomic signatures of empysema and COPD progression in the COPDGene cohortR01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2012 to 2016
$31.1M
(2 of 2) Genetic Epidemiology of COPDR01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2012 to 2016
$18.9M
The clinical impact of pulmonary vascular remodeling in smokersR01HL116473 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SAN JOSE ESTEPAR, RAUL, WASHKO, GEORGE R · 2013 to 2021
$5.0M
Clinical Implications of Bronchiectasis in SmokersR01HL133137 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DIAZ, ALEJANDRO · 2017 to 2021
$2.9M
NHLBI NIH HHS R01 HL089856NHLBI NIH HHS R01 HL089897NHLBI NIH HHS R01 HL116473NHLBI NIH HHS R01 HL133137
6 · The paper itself

Abstract

RATIONALE AND

objectivesBronchiectasis (BE) is associated with chronic obstructive pulmonary disease (COPD), but emphysema and small airways disease, main pathologic features of COPD, have been sparsely studied in BE. We aimed to objectively assess those features in smokers with and without radiographic BE and examine its relationships to airflow obstruction and exercise capacity. MATERIAL AND

methodsWe measured emphysema and small airways disease on paired inspiratory-expiratory computed tomography (CT) scans with the parametric response map (PRM

resultsOut of 1184 subjects, 383 (32%) had radiographic BE. PRM

conclusionSmokers with radiographic BE have an increased burden of emphysema on paired CTs, and those with radiographic BE and emphysema have lower airflow and exercise capacity.

Indexed as

BronchiectasisEmphysemaPulmonary Disease, Chronic ObstructivePulmonary EmphysemaExercise ToleranceForced Expiratory VolumeHumansLungSmokersTomography, X-Ray ComputedBronchiectasisComputed tomographyEmphysemaSix-minute walk testSmall airway disease

Identifiers

PMID32217055
PMCPMC7508820
OpenAlexW3013186051

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.