ArticleBritish journal of anaesthesia2020
A retrospective cohort study on the association between elevated preoperative red cell distribution width and all-cause mortality after noncardiac surgery.
Article in British journal of anaesthesia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- A single postoperative red cell distribution width measurement predicts short- and long-term mortality in surgical patients.Wiener medizinische Wochenschrift (1946) · 2026Article
- Predictors of postoperative survival and mortality in nonagenarian surgical patients: a retrospective cohort study.BMC surgery · 2026Article
- The red cell distribution width (RDW) was associated with preoperative deep venous thrombosis (DVT) in hip fractures: a retrospective study.Perioperative medicine (London, England) · 2026Article
- Elevated preoperative red cell distribution width and incident anemia after metabolic and bariatric surgery: a cohort study.Frontiers in nutrition · 2026Article
- Elevated preoperative red cell distribution width and incident infection after metabolic and bariatric surgery: a cohort study.Frontiers in nutrition · 2026Article
- Risk assessment in cardiac surgery: Exploring machine learning and laboratory indices as adjunctive tools.PloS one · 2026Article
- Early postoperative red cell distribution width is associated with prolonged hospital stay and complications after non-cardiac surgery in neonates.International journal of medical sciences · 2026Article
- Article
- Association between elevated preoperative red cell distribution width and mortality after brain tumor craniotomy.Neurosurgical review · 2024Article
- Red cell distribution width-a potential prognostic indicator for colorectal cancer patients after radical resection in China.Journal of gastrointestinal oncology · 2023Article
- A promising prognostic model for predicting survival of patients with HIV-related diffuse large B-cell lymphoma in the cART era.Cancer medicine · 2023Observational
- Relationship between preoperative red blood cell distribution width and postoperative pneumonia in elderly patients with hip fracture: a retrospective cohort study.Journal of orthopaedic surgery and research · 2023Article
- Is red cell distribution width a prognostic factor in patients with breast cancer? A meta-analysis.Frontiers in surgery · 2023Review
- Higher Preoperative Red Blood Cell Distribution Width Increases the Risk of Myocardial Injury After Noncardiac Surgery in Advanced-Age Patients: A Retrospective Cohort Study.Clinical interventions in aging · 2023Observational
- Association between red blood cell distribution width and mortality in patients with metastatic brain tumors: A retrospective single-center cohort study.Frontiers in oncology · 2022Article
- Risk factors for postoperative pulmonary complications in elderly patients receiving elective colorectal surgery: A retrospective study.Frontiers in oncology · 2022Article
- Exploring red cell distribution width as a potential risk factor in emergency bowel surgery-A retrospective cohort study.PloS one · 2022Article
- Preoperative Routine Laboratory Markers for Predicting Postoperative Recurrence and Death in Patients with Breast Cancer.Journal of clinical medicine · 2021Article
- The use of linked routine data to optimise calculation of the Hospital Frailty Risk Score on the basis of previous hospital admissions: a retrospective observational cohort study.The lancet. Healthy longevity · 2021Observational
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Authors and funding
6 authors.
Funding
Abstract
backgroundElevated red cell distribution width (RDW) has been associated with worse outcomes in several medical patient populations. The aim of this study was to investigate the association of increased preoperative RDW and short- and long-term mortality after noncardiac surgery.
methodsThis investigation was a retrospective cohort study including all patients undergoing noncardiac surgery between 2005 and 2015 at Landspitali-the National University Hospital in Iceland. Patients were separated into five predefined groups based on preoperative RDW (≤13.3%, 13.4-14.0%, 14.1-14.7%, 14.8-15.8%, and >15.8%). The primary outcome was all-cause long-term mortality and secondary outcomes included 30-day mortality, length of stay, and readmissions within 30 days, compared with propensity score matched (PSM) cohort from patients with RDW ≤13.3%.
resultsThere was a higher hazard of long-term mortality for patients with RDW between 14.8% and 15.8% (hazard ratio=1.33; 95% confidence interval, 1.15-1.59; P<0.001) and above 15.8% (hazard ratio=1.66; 95% confidence interval, 1.41-1.95; P<0.001), compared with matched controls with RDW ≤13.3%. This association held in multiple patient subgroups. For secondary outcomes, there was no difference in 30-day mortality, length of stay, or risk of readmission within 30 days.
conclusionsIncreased preoperative RDW is associated with increased long-term mortality after noncardiac surgery. RDW could be a composite biomarker of pre-existing chronic inflammation and poor nutritional status. Future studies should clarify if this is a modifiable risk factor for improved surgical outcomes.
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