Evidence map›Paper›PMID 32216810›Full record

ArticleWorld journal of emergency surgery : WJES2020

Association of pre-operative chronic kidney disease and acute kidney injury with in-hospital outcomes of emergency colorectal surgery: a cohort study.

Katsunori Miyake, Masao Iwagami, Takayasu Ohtake, Hidekazu Moriya, Nao Kume, Takaaki Murata, Tomoki Nishida, Yasuhiro Mochida, Naoko Isogai, Kunihiro Ishioka and 6 more

Open access · goldAbstract read
In one paragraph

Article in World journal of emergency surgery : WJES, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Katsunori MiyakeKidney Disease and Transplant Center, Shonan Kamakura General Hospital, Kanagawa, Japan.
Masao IwagamiDepartment of Health Services Research, University of Tsukuba, Ibaraki, Japan. iwagami-tky@umin.ac.jp.
Takayasu OhtakeKidney Disease and Transplant Center, Shonan Kamakura General Hospital, Kanagawa, Japan.
Hidekazu MoriyaKidney Disease and Transplant Center, Shonan Kamakura General Hospital, Kanagawa, Japan.
Nao KumeDepartment of Surgery, Shonan Kamakura General Hospital, Kanagawa, Japan.
Takaaki MurataDepartment of Surgery, Shonan Kamakura General Hospital, Kanagawa, Japan.
Tomoki NishidaDepartment of Surgery, Shonan Kamakura General Hospital, Kanagawa, Japan.
Yasuhiro MochidaKidney Disease and Transplant Center, Shonan Kamakura General Hospital, Kanagawa, Japan.
Naoko IsogaiDepartment of Surgery, Shonan Kamakura General Hospital, Kanagawa, Japan.
Kunihiro IshiokaKidney Disease and Transplant Center, Shonan Kamakura General Hospital, Kanagawa, Japan.
Rai ShimoyamaDepartment of Surgery, Shonan Kamakura General Hospital, Kanagawa, Japan.
Sumi HidakaKidney Disease and Transplant Center, Shonan Kamakura General Hospital, Kanagawa, Japan.
Hiroyuki KashiwagiDepartment of Surgery, Shonan Kamakura General Hospital, Kanagawa, Japan.
Jun KawachiDepartment of Surgery, Shonan Kamakura General Hospital, Kanagawa, Japan.
Hidemitsu OginoNarita Tomisato Tokushukai Hospital, Chiba, Japan.
Shuzo KobayashiKidney Disease and Transplant Center, Shonan Kamakura General Hospital, Kanagawa, Japan.
Shonan Kamakura General Hospital · JPSuita Tokushukai Hospital · JPTokyo Women's Medical University · JPUniversity of Tsukuba · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPre-operative kidney function is known to be associated with surgical outcomes. However, in emergency surgery, the pre-operative kidney function may reflect chronic kidney disease (CKD) or acute kidney injury (AKI). We examined the association of pre-operative CKD and/or AKI with in-hospital outcomes of emergency colorectal surgery.

methodsWe conducted a retrospective cohort study including adult patients undergoing emergency colorectal surgery in 38 Japanese hospitals between 2010 and 2017. We classified patients into five groups according to the pre-operative status of CKD (defined as baseline estimated glomerular filtration rate < 60 mL/min/1.73 m

resultsWe identified 3002 patients with emergency colorectal surgery (mean age 70.3 ± 15.4 years, male 54.5%). The in-hospital mortality was 8.6% (169/1963), 23.8% (129/541), 15.3% (52/340), 28.8% (17/59), and 32.3% (32/99) for CKD(-)AKI(-), CKD(-)AKI(+), CKD(+)AKI(-), CKD(+)AKI(+), and ESRD, respectively. Other outcomes such as blood transfusion and post-operative renal replacement therapy showed similar trends. Compared to the CKD(-)AKI(-) group, the adjusted odds ratio (95% confidence interval) for in-hospital mortality was 2.54 (1.90-3.40), 1.29 (0.90-1.85), 2.86 (1.54-5.32), and 2.76 (1.55-4.93) for CKD(-)AKI(+), CKD(+)AKI(-), CKD(+)AKI(+), and ESRD groups, respectively. Stratified by baseline eGFR (> 90, 60-89, 30-59, and < 30 mL/min/1.73 m

conclusionsThe differentiation of pre-operative CKD and AKI, especially the identification of AKI, is useful for risk stratification in patients undergoing emergency colorectal surgery.

Indexed as

Acute Kidney InjuryAgedColonic DiseasesEmergenciesFemaleHospital MortalityHumansJapanKidney Function TestsMaleRectal DiseasesRenal Insufficiency, ChronicRetrospective StudiesRisk FactorsAcute kidney injuryChronic kidney diseaseColorectal surgeryEmergency surgeryEnd-stage renal disease

Identifiers

PMID32216810
PMCPMC7098074
OpenAlexW3013226847

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.