SynthesisLipids in health and disease2020
Monocyte to High-Density Lipoprotein Ratio (MHR) as a predictor of mortality and Major Adverse Cardiovascular Events (MACE) among ST Elevation Myocardial Infarction (STEMI) patients undergoing primary percutaneous coronary intervention: a meta-analysis.
Synthesis in Lipids in health and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Accuracy of Machine Learning Models for Early Prediction of Major Cardiovascular Events Post Myocardial Infarction: A Systematic Review and Meta-Analysis.Reviews in cardiovascular medicine · 2025Pooled it
- The association between high-density lipoprotein-related inflammation index and female infertility prevalence: Insight from a cross-sectional study of NHANES.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Monocyte-to-High-Density-Lipoprotein Ratio Is Associated with Ventricular Arrhythmia in Patients with Implantable Cardioverter-Defibrillators: A Cross-Sectional Study.Journal of cardiovascular development and disease · 2026Article
- Article
- Retrospective cohort study: association of Monocyte/HDL cholesterol ratio with early mortality in patients undergoing sutureless aortic valve replacement for aortic stenosis.Journal of cardiothoracic surgery · 2026Article
- Investigating the relationship between monocyte to high-density lipoprotein cholesterol ratio and carotid artery plaque in cerebral infarction patients under different blood pressure and glucose metabolic conditions.Lipids in health and disease · 2026Article
- Imbalances in circulating monocyte and high-density lipoprotein cholesterol exacerbates the residual risk of incident myocardial infarction beyond LDL-C: a real-life, prospective cohort study.Journal of translational medicine · 2025Article
- Association of Inflammation-Based Ratios with Endothelial Dysfunction Markers and Clinical Parameters in Limited Cutaneous Systemic Sclerosis.Journal of clinical medicine · 2025Article
- Serum soluble transferrin receptor (sTfR) in HFpEF: associations with cardiac function and exercise tolerance.European journal of medical research · 2025Article
- Monocyte-to-HDL ratio (MHR) as a novel biomarker: reference ranges and associations with inflammatory diseases and disease-specific mortality.Lipids in health and disease · 2025Article
- Metabolic and Inflammatory Biomarkers Predicting Sarcopenic Obesity and Cardiometabolic Risk in Arab Women: A Cross-Sectional Study.International journal of molecular sciences · 2025Article
- Study of Monocyte-High Density Lipoprotein ratio to coronary artery diameter in coronary heart disease patients.Global cardiology science & practice · 2025Article
- Establishing and internally validating a predictive model for coronary heart disease incorporating triglyceride-glucose index, monocyte-to-high-density lipoprotein cholesterol ratio and conventional risk factors in patients experiencing chest pain and referred for invasive coronary angiography.Lipids in health and disease · 2025Article
- Monocyte to High-Density Lipoprotein Ratio Is Associated With Carotid Plaque: A Retrospective Cohort Study.Journal of the American Heart Association · 2025Article
- Correlation Between Triglyceride-Glucose Index (TyG Index), Monocyte to High-Density Lipoprotein Cholesterol Ratio (MHR), and the Severity of Coronary Artery Disease.International journal of general medicine · 2025Article
- Updated focused review of hematological, inflammatory, and lipid biomarkers in acute coronary syndrome.Archives of medical science : AMS · 2025Article
- Evaluation of the prognosis of elderly patients with heart failure by Monocyte-to-High-Density Lipoprotein Ratio, Neutrophil Gelatinase-Associated Lipocalin, and Angiotensin II.Frontiers in cardiovascular medicine · 2025Article
- Nonlinear Association Between Monocyte-to-HDL Ratio and Mortality in COPD: Evidence from NHANES.International journal of chronic obstructive pulmonary disease · 2025Article
- Association between monocyte to high-density lipoprotein cholesterol ratio and telomere length: based on NHANES 1999-2002.BMC cardiovascular disorders · 2024Article
- Monocyte Count as a Predictor of Major Adverse Limb Events in Aortoiliac Revascularization.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMonocyte to High Density Lipoprotein Ratio (MHR) is a new marker that has been associated with major adverse cardiovascular outcomes among STEMI patients. We sought to strengthen the association between MHR and mortality and major adverse cardiovascular events (MACEs) among STEMI patients who underwent primary percutaneous coronary intervention.
methodsStudies were included if they satisfied the following criteria:1) Observational Studies; 2) Adult patients with ST-elevation Myocardial Infarction (STEMI) who underwent primary percutaneous intervention (PCI); and 3) Reported data on mortality and major adverse cardiovascular events. Using MEDLINE, Clinical Key, Science Direct, Scopus, and Cochrane Central Register of Controlled Trials databases, a search for eligible studies was conducted until September 2017. Our primary outcome of interest was all-cause cardiovascular (CV) mortality. We also investigated the association between MHR and major adverse cardiovascular events (MACEs).
resultsWe identified 3 studies involving 2793 STEMI patients, showing that in STEMI patients who underwent primary PCI, a high admission MHR is associated with a significantly higher in-hospital mortality [RR 4.71, (95% CI 2.36 to 9.39, p < 0.00001] and in-hospital MACE [RR 1.90, (95% CI 1.44 to 2.50), p < 0.00001]. This significant association was not observed in long term mortality or MACE.
conclusionA high admission MHR among STEMI patients who underwent primary PCI is associated with a higher in-hospital mortality and MACE. This novel marker can be used as an inexpensive and readily available tool for risk stratification.
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