Evidence map›Paper›PMID 32216785›Full record

ArticleBMC women's health2020

Prevalence of Mycoplasma genitalium infection in women with bacterial vaginosis.

Melinda B Nye, Ayla B Harris, Amanda J Pherson, Charles P Cartwright

Open access · goldAbstract read
In one paragraph

Article in BMC women's health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Influence of cervicovaginal microbiota onMicrobial cell (Graz, Austria) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Frontiers in microbiology · 2023
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Melinda B NyeCenter for Esoteric Testing, Laboratory Corporation of America® Holdings, Burlington, North Carolina, USA.
Ayla B HarrisCenter for Esoteric Testing, Laboratory Corporation of America® Holdings, Burlington, North Carolina, USA.
Amanda J PhersonCenter for Esoteric Testing, Laboratory Corporation of America® Holdings, Burlington, North Carolina, USA.
Charles P CartwrightSpeeDx Pty. Ltd., Sydney, Australia. charlesc@speedx.com.au.
LabCorp (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBacterial vaginosis (BV) is a common condition in reproductive-age women and is known to be positively associated with risk of acquisition of sexually transmitted infections (STI) such as chlamydia and gonorrhea. Mycoplasma genitalium is an emerging STI that has been linked to increased risk of pelvic inflammatory disease, adverse pregnancy outcomes and infertility. In the present study we sought to examine whether women diagnosed with symptomatic BV were at increased risk of having concurrent infection with Mycoplasma genitalium.

methodsWe used a novel PCR-based assay (ResistancePlus MG; SpeeDx Pty. Ltd., Sydney, Australia) to determine the prevalence of Mycoplasma genitalium infection and 23S rRNA macrolide-resistance mediating mutations (MRMM) in a cohort of 1532 women presenting with symptoms of vaginitis.

resultsM. genitalium was detected in 4.0% (62/1532) of samples with 37.1% (23/62) harboring MRMMs. The prevalence of M. genitalium infection in subjects with BV was significantly higher than in subjects with non-BV vaginitis (7.0% v 3.6%; OR = 1.97 (95% CI: 1.14-3.39).

conclusionsPrevalence of M. genitalium infection is associated with BV in women with symptomatic vaginitis. Improved management of BV is needed as a component of STI prevention strategies.

Indexed as

AdolescentAdultAnti-Bacterial AgentsAustraliaFemaleHumansMacrolidesMicrobial Sensitivity TestsMiddle AgedMycoplasma genitaliumMycoplasma InfectionsPolymerase Chain ReactionPregnancyPrevalenceVaginosis, BacterialYoung AdultAnti-Bacterial AgentsMacrolidesAntimicrobial resistanceAssociationBacterial vaginosisMycoplasma genitaliumPrevalence

Identifiers

PMID32216785
PMCPMC7099815
OpenAlexW3013232009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.