SynthesisBritish journal of clinical pharmacology2020
Generic instruments for drug discontinuation in primary care: A systematic review.
Synthesis in British journal of clinical pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Generic instruments for drug discontinuation in primary care: A systematic review.British journal of clinical pharmacology · 2020Pooled it
- Opioid Therapy Discontinuation in General Practice: Associations with Adjunct Therapies and Somatoform Pain Disorders.Drugs - real world outcomes · 2026Article
- Functional Deprescribing: A Systems-Based Framework for Safe Medication Reduction.Integrative medicine (Encinitas, Calif.) · 2026Article
- Adaptive questionnaires for facilitating patient data entry in clinical decision support systems: methods and application to STOPP/START v2.BMC medical informatics and decision making · 2024Article
- Defining, identifying and addressing problematic polypharmacy within multimorbidity in primary care: a scoping review.BMJ open · 2024Article
- MediQuit - an electronic deprescribing tool: a pilot study in German primary care; GPs' and patients' perspectives.BMC primary care · 2022Article
- MediQuit, an Electronic Deprescribing Tool for Patients on Polypharmacy: Results of a Feasibility Study in German General Practice.Drugs & aging · 2021Article
- Professional roles of general practitioners, community pharmacists and specialist providers in collaborative medication deprescribing - a qualitative study.BMC family practice · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
aimsThe aim of this systematic review was to identify generic instruments for drug discontinuation in patients with polypharmacy in the primary care setting.
methodsWe systematically searched PubMed and EMBASE, 8 guideline databases (AWMF, NICE, NGC, SIGN, NHMRC, CPG, KCE), the Cochrane Library and grey literature (Google) in 2016 and 2017. Two independent researchers screened and analysed data. The drug discontinuation instruments of the included publications were described and classified.
resultsWe identified 16 relevant publications. Here we found complex algorithms as well as instruments composed of distinct sequential steps. Two guidelines are constructed as electronic web-applications. Instruments revealed diverging emphases on the stages of deprescribing, i.e. preparation, drug evaluation, decision-making and implementation. Accordingly, 3 types of instruments emerged: general frameworks, detailed drug assessment tools and comprehensive discontinuation guidelines.
conclusionDiverse generic instruments exist for different areas of applications in regard to drug discontinuation. However, there is still a need for practical and user-friendly tools that support physicians in communicational aspects, visualise trade-offs and also enhance patient involvement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.