ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2020
Does the network model fits neurophysiological abnormalities in blepharospasm?
Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Predictors of cognitive performance in idiopathic adult-onset dystonia.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Phenotypic comparison between combined dystonia-parkinsonism and idiopathic adult-onset dystonia.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Brain functional network topology and connectivity in primary blepharospasm.Frontiers in systems neuroscience · 2025Article
- Spontaneous neural activity alterations in medication-naïve primary blepharospasm: a resting-state functional magnetic resonance imaging study.Frontiers in systems neuroscience · 2025Article
- Phenotypic Variability in Acquired and Idiopathic Dystonia.Movement disorders clinical practice · 2023Article
- Elucidation of the mechanism underlying impaired sensorimotor gating in patients with primary blepharospasm using prepulse inhibition.Frontiers in neurology · 2023Article
- Functional connectivity alterations in the frontoparietal network and sensorimotor network are associated with behavioral heterogeneity in blepharospasm.Frontiers in neurology · 2023Article
- The pathogenesis of blepharospasm.Frontiers in neurology · 2023Review
- Thalamic structural connectivity profiles in blepharospam/Meige's syndrome.NeuroImage. Clinical · 2022Article
- Smell and taste in idiopathic blepharospasm.Journal of neural transmission (Vienna, Austria : 1996) · 2021Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several neurophysiological abnormalities have been described in blepharospasm, including loss of inhibition in sensorimotor pathways at cortical and brainstem level and abnormalities of sensory processing. These changes have traditionally been linked to a basal ganglia dysfunction. However, this interpretation has recently been questioned and alternative pathophysiological model positing that dystonia is a network disorder has been proposed. On the basis of available information, we can speculate that loss of inhibition at cortical and brainstem level and abnormalities of sensory processing in blepharospasm probably reflect the functional derangement of a network involving frontal and parietal cortical areas, basal ganglia, thalamus, and, possibly, the cerebellum.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.