ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020
The impact of metabolic syndrome on mental health-related quality of life and depressive symptoms.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Is greater adherence to the Mediterranean diet related to higher health-related quality of life among children and adolescents? A systematic review and meta-analysis.European journal of pediatrics · 2025Pooled it
- Association of metabolic syndrome and its components with the risk of depressive symptoms: A systematic review and meta-analysis of cohort studies.Journal of affective disorders · 2023Pooled it
- Influence of Early Postoperative Basal Insulin Treatment and Post-Transplant Diabetes Mellitus Risk on Health-Related Quality of Life in Kidney Transplant Recipients-An Analysis of Data From a Randomized Controlled Trial.Transplant international : official journal of the European Society for Organ Transplantation · 2023Trial
- Associations Between Triglycerides and Walking Capacity in Community-Dwelling Older Adults with Metabolic Syndrome.Diseases (Basel, Switzerland) · 2026Article
- Study protocol on effectiveness of a holistic lifestyle intervention using eHealth system for older adults with metabolic syndrome and psychosomatic symptoms: a randomized controlled trial.BMC geriatrics · 2025Article
- Metabolic syndrome and health-related quality of life: unraveling the role of gender (A SUMS employees cohort-based study).BMC research notes · 2025Article
- Metabolic syndrome increases the risk of suicide attempt: evidence from a population-based cohort and genomic analysis.Translational psychiatry · 2025Article
- Anti-Müllerian Hormone Levels Are Associated With Skeletal Maturity in Adolescent Girls: A Longitudinal Study.Health science reports · 2025Article
- Effect of liraglutide on depressive symptoms in overweight or obese patients with type 2 diabetes: protocol for a pilot randomized controlled trial.Frontiers in endocrinology · 2025Article
- Metabolic syndrome.Nature reviews. Disease primers · 2024Review
- Association between type 2 diabetes and depressive symptoms after a 1-year follow-up in an older adult Mediterranean population.Journal of endocrinological investigation · 2024Article
- Quality of Life in Metabolic Syndrome Patients Based on the Risk of Obstructive Sleep Apnea.Behavioral sciences (Basel, Switzerland) · 2024Article
- Effects of Metabolic Syndrome and Sex on Stress Coping Strategies in Individuals with Depressive Disorder.Metabolites · 2023Article
- Changes in Depressive Symptoms, Perceived Stress, and Food Security Among Study Participants With Metabolic Syndrome During a COVID-19-Mandated Research Pause.Preventing chronic disease · 2022Article
- Article
- A prospective registry analysis of psychosocial and metabolic health between women with and without metabolic syndrome after a complicated pregnancy.BMC women's health · 2022Article
- Association between Dietary Patterns Reflecting C-Reactive Protein and Metabolic Syndrome in the Chinese Population.Nutrients · 2022Article
- Hepatic Fibrosis and Steatosis in Metabolic Syndrome.Journal of obesity & metabolic syndrome · 2022Article
- Frailty and Quality of Life in Older Adults with Metabolic Syndrome - Findings from the Healthy Older People Everyday (HOPE) Study.The journal of nutrition, health & aging · 2021Article
- Relationship between Metabolic Syndrome and Mental Health Status among Geriatric Females: A Cross-sectional Study.Journal of mid-life healthArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
purposeResults examining associations between metabolic syndrome (MetS) and depression, as well as on quality of life (QoL), are inconsistent. We aimed to determine whether individuals with MetS had decreased mental health-related QoL (MH-QoL) and higher frequency of depressive symptoms.
methodsData from 1,015 participants from the Fels Longitudinal Study were analyzed (mean age ± SD: 49.6 ± 18.7 years, 29.3% MetS, 51% females). MetS was determined using American Heart Association/National Heart, Lung, and Blood Institute criteria. Depressive symptoms (yes vs. no) were assessed with The Patient Health Questionnaire-9 (PHQ-9). MH-QoL (low (≤ 42) vs. high) was assessed with The Medical Outcomes 36-Item Short Form Survey (SF-36). Sex- and age-stratified mixed effects logistic regressions were used to examine the longitudinal relationship between MetS and MH-QoL while adjusting for covariates such as age, smoking status, and drinking status.
resultsIn cross-sectional analysis, MetS was significantly associated with elevated depressive symptoms in women (OR 2.14, 95% CI 1.22-3.78, p < 0.01), but not in men. In the longitudinal analysis, MetS was observed to have a protective effect among men in the older age group as it approached significance (OR 0.34, 95% CI 0.11-1.05, p = 0.06).
conclusionMetS was adversely associated with depressive symptoms and poor MH-QoL. Our cross-sectional results suggest that depressive symptoms are higher among women with MetS. Interestingly, our longitudinal results suggest that MH-QoL in men with MetS may improve with age.
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